摘要
冠状动脉支架内新生动脉粥样硬化斑块(ISNA)形成可能是导致晚期血管并发症如支架内再狭窄(ISR)及晚期支架内血栓(LST)形成的重要原因,虽然支架内血栓发生率较低,但一旦发生将带来严重后果,具有很高的死亡率。ISNA形成不仅涉及第一代药物洗脱支架(DES),而且第二代DES也不能完全幸免。迄今为止,关于ISNA的发生机制仍不清楚,且尚无有效的干预措施。
In-stent neoatherosclerosis has emerged as an important contributing factor to late vascular complications including late in-stent restenosis and late stent thrombosis. Stent thrombosis is an uncommon but serious complication and associated with a high mortality. The development of in-stent neoatherosclerosis has been identified not only in first-generation DES, but also in second-generation DES. Currently, the precise mechanism of neoatherosclerosis development remains unknown and there is no effective intervention measures.
出处
《中国医学创新》
CAS
2015年第34期153-156,共4页
Medical Innovation of China
基金
贵州省科学技术基金(黔科合J字LKz(2011)50)
