摘要
缺血性脑血管病的发生与诸多因素相关,而中医则认为"气虚血瘀"为其主要病机之一。目前,临床治疗多以益气活血作为本类疾病的基本治疗原则,益气活血法在临床上被广泛用于脑缺血的治疗,并取得了显著效果。益气活血方药,因其成分的复杂性,显示多层次、多环节及多靶点的作用优势。为此,综合论述近年来的相关文献,从保护神经元、促神经再生、改善能量代谢、降低兴奋毒性以及改善微循环等方面系统总结益气活血法防治缺血性脑血管病的作用机制,以期为临床应用提供现代药理学理论依据。
The occurrence of ischemic cerebrovascular disease related to many factors, TCM believes that‘qi deficiency blood stasis＇ is one of the main pathogenesis. In clinical treatment, yiqi huoxue is as a basic therapeutic principle for this kind of disease, yiqi huoxue method is widely used for treatment of cerebral ischemia in clinic,it has been achievedsignificantresults.Yiqi huoxue fang yao shows action advantage of multiple evel, multiple stage, multiple targets, because of the complexity of its composition. Inthis paper,related literaturesare reviewed in recent years,it systematically summarizedthe action mechanism of yiqi huoxue fa for prevention and treatment of ischemiccerebrovascular disease, from the protection of neurons, promoting the nerve regeneration, improving the energy metabolism, reducing the toxicity of excitement, improving microcirculation,so as to provide modern pharmacology theoretical basis for its clinical application.
出处
《中国医学装备》
2016年第1期122-126,共5页
China Medical Equipment
基金
国家自然科学基金青年基金(81403288)"基于脑缺血动物模型的"肾通于脑"中医理论的生物学实质研究"
黑龙江省自然科学基金(QC2015102)"基于脑缺血动物模型的"肾通于脑"中医理论的生物学实质研究"
黑龙江省政府博士后资助基金(LBHZ13200)"针刺补肾改善性腺切除动物记忆障碍的机制研究"
关键词
益气活血
脑缺血
气虚血瘀
Yiqi huoxue
Cerebral ischemia
Qi deficiency and blood stasis
