摘要
目的:探讨依那普利治疗农村高血压患者的临床疗效。方法:149例农村高血压患者随机分为依那普利组(74例)和卡托普利组(75例),卡托普利组给予卡托普利25mg口服(3次/天),依那普利组予以依那普利10mg口服(1次/天),记录两组患者退出治疗的例数,治疗前、治疗后2周和8周的血压值。结果:依那普利组和卡托普利组退出治疗的比例分别为16.2%(12/74)和30.7%(23/75),依那普利组明显低于卡托普利组(P<0.05)。两组治疗后2周和8周的血压明显低于治疗前(P<0.05),但组间比较差异无统计学意义(P>0.05)。结论:依那普利治疗农村高血压患者的降压效果与卡托普利相当,具有依从性好、不良反应少等优点。
Objective：To investigate the curative effects for treating rural hypertension patients with enalapril.Methods：149 rural hypertension patients were randomly divided into enalapril group（n=74,enalapril 25 mg,qd） and captopril group（n=75,captopril lOmg,tid）.The number of patients out of treatment in 2 groups,the blood pressure of patients before treatment,2 weeks and 8 weeks after treatment were respectively recorded.Results：The ratio of patients out of treatment in enalapril group was 16.2%（12/74）,which was obviously lower than captopril group（30.7%,P〈0.05）.Compared with that before treatment,the blood pressure of patients in 2 groups 2 weeks and 8 weeks after treatment decreased obviously（P〈0.05）;But there was no significant difference between enalapril group and captopril group about blood pressure after treatment（P〉0.05）.Conclusions：Treating rural hypertension patients with enalapril can get antihypertensive effects as captopril,and has the advantages of better compliance and fewer adverse reactions.
出处
《承德医学院学报》
2016年第1期25-27,共3页
Journal of Chengde Medical University
