摘要
目的调查北京市丰台区方庄社区70岁以上老年男性原发性骨质疏松症（OP）患病率及其相关的临床危险因素。方法根据入选和排除标准于2014年1—10月在北京市丰台区方庄社区采用广告招募的抽样方法,收集接受双能X线骨密度仪骨密度检查并完成《北京市老年男性原发性骨质疏松症高危人群临床危险因素调查问卷》调查的北京地区70岁以上老年男性人群150例。测量并记录所有患者的腰椎总（L1~4）、左侧股骨颈和左侧髋部总的骨密度值。根据WHO诊断标准诊断OP患者,将研究对象分为OP组和非OP组,分析各临床危险因素与OP发生的相关性。结果 150例老年男性OP患病率为20.7%（31/150）,骨量减少者占55.3%（83/150）,骨量正常者占24.0%（36/150）。150例老年男性腰椎总骨密度、左侧股骨颈骨密度、左侧髋部总骨密度比较,差异有统计学意义（F=96.106,P〈0.001）;其中腰椎总骨密度高于左侧股骨颈骨密度和左侧髋部总骨密度,左侧股骨颈骨密度高于左侧髋部总骨密度,差异均有统计学意义（P〈0.001）。OP组和非OP组吸烟史、饮酒史、既往骨折病史、糖尿病史、饮茶、饮咖啡、饮碳酸饮料、食用醋情况比较,差异均无统计学意义（P〉0.05）;OP组和非OP组体质指数和体质量比较,差异有统计学意义（P〈0.05）。以体质量评价OP时,AUC值为0.701,最佳诊断截断值为70.0 kg,灵敏度为48.7%,特异度为83.9%;以体质指数评价OP时,AUC值为0.661,最佳诊断截断值为23.8 kg/m2,灵敏度为62.2%,特异度为74.2%。结论方庄社区70岁以上老年男性OP患病情况不容忽视,低体质指数和低体质量是OP相关的临床危险因素,其中体质量因素有中度预测价值,但有待进一步深入研究。
Objective To investigate the osteoporosis prevalence and osteoporosis-related clinical risk factors among elderly male aged over 70 in Beijing Fangzhuang Community in Fengtai District. Methods Using sampling method of recruitment advertising,we enrolled 150 elderly male aged over 70 from Beijing Fangzhuang Community according to inclusion and exclusion standard from January to October in 2014. Bone mineral density（ BMD） of the subjects was tested by dual-energy X-ray absorptiometry（ DXA）,and the questionnaire of clinical risk factors for elderly males with high risk for osteoporosis in Beijing was completed by the subjects. The bone mineral density of L1-4,left femoral neck and left total hip were measured and recorded. According to the WHO diagnostic criteria,OP patients were diagnosed and were divided into OP group and non-OP group. Correlation between clinical risk factor and the occurrence of OP was analyzed. Results Among the 150 subjects,20. 7%（ 31 /150） had osteoporosis,55. 3%（ 83 /150） had osteopenia and 24. 0%（ 36 /150） had normal bone mass. The150 subjects were significantly different in the total bone mineral density of lumbar vertebrae,bone mineral density of left femur and the total bone mineral density of hip（ F = 96. 106,P 0. 001）; the total bone mineral density of lumbar vertebrae was higher than bone mineral density of left femur and the total bone mineral density of hip（ P 0. 001 for both）,and bone mineral density of left femur was higher than left the total bone mineral density of hip（ P 0. 001）. OP group and non-OP group were significantly different in the history of smoking, alcohol consumption, bone fracture, and diabetes, tea drinking, coffee drinking,carbonated beverage and the consumption of table vinegar（ P 0. 05）; the two groups were significantly different in BMI and body mass（ P 0. 05 for both）. For the assessment of OP by body mass,the AUC was 0. 701,the best diagnostic cut-off value was 70. 0 kg,the sensitivity was 48. 7%,and the specificity w
出处
《中国全科医学》
CAS
CSCD
北大核心
2015年第35期4344-4348,共5页
Chinese General Practice
基金
2013北京市科学技术委员会(Z131100006813040)--首都市民健康项目培育
