急性冠状动脉综合征患者血清胆红素浓度的变化与临床意义被引量：2

下载PDF

导出

摘要目的探讨急性冠状动脉综合征(ACS)患者血清胆红素浓度变化及临床意义。方法检测84例不稳定心绞痛(UAP)和72例急性心肌梗死(AMI)患者急性发病期总胆红素(TBil)、直接胆红素(DBil)和间接胆红素(IBil)浓度,比较它们的差异。结果 UAP组和AMI组TBil、IBil浓度与对照组比较差异有极显著性意义(P<0.01),AMI组IBil明显高于UAP组差异有显著性意义(P<0.05),三组DBil差异无显著性意义(P>0.05)。结论血清胆红素浓度变化与冠脉斑块活动相关,它对ACS发生的预测、诊断和防治有一定临床意义。

作者吴泽奎荣根满

机构地区辽宁省抚顺市第二医院循环内科中铁十九局集团中心医院医务科

出处《中国医药指南》 2016年第1期104-105,共2页 Guide of China Medicine

关键词急性冠状动脉综合征血清胆红素抗氧化剂

分类号 R542.22 [医药卫生—心血管疾病]

引文网络
相关文献

参考文献13

1Schwerther HA,Jackson WG,Tolan G.Association of low serum concentration of bilirubin with increased risk of coronary artery disease[J].Clin Chem,2009,55(1):18-23. 被引量：1
2Cao G,Alessio HM,Cutler RG.Oxygen radical absorbance capacity assay for antioxidants[J].Fre Rad Biol Med,2009,30(1):303-311. 被引量：1
3Stocked R,Mcdonagh AF,Glazer AN,et al.Antioxidant ac2 tivities of bile pigments:biliverdin and bilirubin[J].Methods Enzymol,2010,206(2):301-306. 被引量：1
4Nakagami T,Toyomuna K,Kinoshita T,et al.A beneficial role of bile pigmengts as an endogenous tissue protector:Anti2 complement effects of biliverdin and conjugated bilirubin[J].Biochem Biophys Acta 2009,1174(1):189-193. 被引量：1
5Bremer LH,Wannamethee G,Ebrahim S,et al.Serum biliru2 bin and risk of ischemic heart disease in middle aged Britishmen[J].Clin Chem 2010,56(10):1504. 被引量：1
6Mar r ilema G.New physiological impor tance of t wo classic residual products:carbon monoxide and bilirubin[J].Biochem Mol Med,2009,73(2):136-142. 被引量：1
7Terry CM,Jennifer A,Clickeman JR.Effect of tumor necrosis factor2αand interleukin21αon heme oxygenase-1 expression in human endothelial cells[J].Am J Physiol,2010,286(5):883-891. 被引量：1
8Morita T,Kourembanas S.Endothelial cell expression of vaso2concentrictors and growth factors is regulated by smooth muscle cell2derived carbon monoxide[J].J Clin Invest,2010,117(10):2676-2682. 被引量：1
9Hopkins PN,Wu LL,Hunt SC,et al.Higher ser um bilir ubin is associated with decreased risk for early familial coronary artery disease[J].Arterioscler Thromb Vasc Biol,2010,30(2):254-255. 被引量：1
10成晋锋,王雄.血清尿酸和胆红素与急性冠状动脉综合征的关系[J].中国医疗前沿,2011,6(22):32-33. 被引量：5

二级参考文献29

1田乃亮,陈绍良,马玉玲,刘志忠,段宝祥.血清尿酸和胆红素在急性冠状动脉综合征患者中的变化及意义[J].临床荟萃,2005,20(7):379-381. 被引量：32
2薛丽,张爱伦.血尿酸与冠心病的关系及其机制的研究进展[J].心血管病学进展,2006,27(1):50-52. 被引量：14
3张建英,杨平,李益强,祁丕东.他汀类药物除调脂作用外的临床有益作用[J].中国药业,2006,15(2):80-80. 被引量：9
4李守霞,赵素斌,杨建英,秦冰.冠心病患者血清胆红素、尿酸水平含量及临床价值[J].临床荟萃,2006,21(7):482-483. 被引量：13
5胡大一,马长生.心脏病实践[M].北京:人民卫生出版社,2003:23-31. 被引量：4
6Schwertner HA,Jackson WG,Tolan G,et al.Association of low serum concentration of bilirubin with increased risk of coronary artery disease[J].Clin chen,1994,40(1):18-23. 被引量：1
7Albert MA,Danielson E,Rifai N,et al.Effect of statin therapy on Creactive protein levels:the pravastin inflammation/CRP evaluation (PRINCE):a randomized trial and cohort study[J].JAMA,2001,286(1):64-70. 被引量：1
8Mulvihill NT,Foley JB.Inflammation in acute coronary syndroms[J].Heart,2002,87(3):201-204. 被引量：1
9Verma S,Li SH,Badiwala MV,et al.Endothelin antagonism and interleukin-6 inhibition attennate the proatherogenic effects of Creactive protein[J],Circulation,2002,105(16):1890-1896. 被引量：1
10Madhavan M,Wattigney WA,Srinivasan SR,et al.Serum bilirubin distribution and its relation to cardiovascular risk in children and young adults[J].Atherosclerosis,1994,131(4):107-113. 被引量：1