摘要
目的了解上海市艾滋病病毒（HIV）抗体阴性的男男性行为人群（men who have sex with men,MSM）中乙型肝炎病毒（hepatitis B virus,HBV）和丙型肝炎病毒（hepatitis C virus,HCV）感染现况及其影响因素。方法以上海市为现场招募HIV抗体阴性的MSM人群,收集人口学及行为学信息,进行HBV表面抗原（hepatitis B surface antigen,HBs Ag）和HCV抗体（hepatitis C surface antibody,HCVAb）检测。结果共招募983名HIV抗体阴性MSM,HBs Ag阳性率为10.8%（95%CI：9.1%-12.5%）,HCVAb阳性率为0.2%。多因素Logistic回归分析显示,少数民族的HBs Ag阳性率高于汉族（OR=3.04,95%CI：1.23-7.52）,而大学及以上文化程度者的HBs Ag阳性率则低于初中及以下文化程度者（OR=0.39,95%CI：0.22-0.70）。结论上海市HIV抗体阴性MSM的HBV感染率较高而HCV感染率与一般人群接近,提示有必要加强MSM人群特别是少数民族和低学历者的乙型肝炎相关健康宣教乃至HBV免疫接种等预防措施。
Objectives To examine seroprevalence and correlates of hepatitis B virus（ HBV） and hepatitis C virus（ HCV） among HIV-negative MSM in Shanghai. Methods A serological study for HBV and HCV in HIV-negative MSM was performed in Shanghai. Participants were interviewed and screened for hepatitis B virus surface antigen（ HBs Ag）and hepatitis C virus antibody（ HCVAb）. Results 983 HIV-negative MSM participated in the study. The seroprevalence of HBs Ag was 10. 8%（ 95% CI： 9. 1%-12. 5%） and the seroprevalence of HCVAb was 0. 2%. Multiple logistic regression analysis indicated that HBV infection was more likely to occur among participants who were ethnic minorities（ OR = 3. 04,95% CI： 1. 23-7. 52）. Otherwise,HBV infection was less likely to occur among participants with a bachelor degree or above（ OR = 0. 39,95% CI： 0. 22-0. 70）. Conclusions HIV-negative MSM in Shanghai has a relatively high seroprevalence of HBs Ag but relatively low seroprevalence of HCVAb. More efforts are needed to strengthen HBV health education and immunization programs among this population,especially MSM with ethnic minority and low education.
出处
《中华疾病控制杂志》
CAS
CSCD
北大核心
2015年第12期1223-1226,共4页
Chinese Journal of Disease Control & Prevention
基金
"十二五"国家科技重大专项(2012ZX10001007-006)
