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计算代数在不稳定酶动力系统分析中的应用

The application of computational algebra in the analysis of unstable enzyme kinetics systems
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摘要 对最简单的不稳定酶动力系统进行动力学分析,并给出了酶动力系统的数学模型-常微分方程组。在初始酶浓度远远大于底物浓度的假设下,利用计算代数理论,求出了数学模型的符号解,最后通过例子来证明本文所用方法的准确性和有效性。 In this paper,we study the kinetic analysis of unstable enzymatic systems,and present a mathematical model-involving system of ordinary differential equations. Under the assumption that the initial enzyme concentration is far greater than the initial substrate concentration,using the theories of computer algebra,we obtain the analytical solutions of the mathematical model. Finally,some examples are given to illustrate the validity and efficiency of the method developed in this paper.
出处 《北京化工大学学报(自然科学版)》 CAS CSCD 北大核心 2015年第5期117-119,共3页 Journal of Beijing University of Chemical Technology(Natural Science Edition)
基金 国家自然科学基金(11101029) 中央高校基本科研业务费(610806)
关键词 不稳定酶动力系统 动力学分析 计算机代数 MAPLE 线性系统 unstable enzyme kinetics system kinetic analysis computer algebra Maple linear system
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参考文献10

  • 1English Brian P,Min Wei,van Oijen Antoine M,Lee Kang Taek,Luo Guobin,Sun Hongye,Cherayil Binny J,Kou S C,Xie X Sunney.Ever-fluctuating single enzyme molecules: Michaelis-Menten equation revisited. Nature chemical biology . 2006 被引量:1
  • 2Eisenthal P,Cornish-Bowder A.The direct linear plot. A new graphical procedure for estimating enzyme kinetic parameters. Biochemical Journal . 1974 被引量:1
  • 3Cornish-Bowden A.The use of the direct linear plot for determining initial velocities. The Biochemical Journal . 1975 被引量:1
  • 4Bell L C,Guengerich F P.Oxidation kinetics of ethanol by human cytochrome P450 2E1. Rate-limiting product release accounts for effects of isotopic hydrogen substitution and cytochrome b5 on steady-state kinetics. Journal of Biological Chemistry . 1997 被引量:1
  • 5Briggs G E,Haldane J B.A Note on the Kinetics of Enzyme Action. The Biochemical Journal . 1925 被引量:1
  • 6L. A. Segel,M. Slemrod.The quasi-steady state assumption: a case study in perturbation. SIAM Review . 1989 被引量:1
  • 7Cornish-Bowden A.Fundamentals of Enzyme Kinetics. . 1995 被引量:1
  • 8Banghe Li,Yuefeng Shen,Bo Li.Quasi-Steady-State Laws in Enzyme Kinetics. Journal of Physics . 2008 被引量:1
  • 9Voet D,Voet J G,Pratt C W.Fundamentals of biochemistry. . 1999 被引量:1
  • 10Brown A J.Enzyme action. Journal of the American Chemical Society . 1902 被引量:1

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