摘要
目的探讨开喉剑喷雾剂治疗儿童急性咽喉炎的有效性和安全性。方法选取2014年5月至2015年1月因儿童急性咽喉炎在我科就诊的患儿160例,采取随机数字表法分为观察组与对照组,每组各80例,两组均给予常规治疗,观察组给予开喉剑喷雾剂,对照组给予咽扁冲剂。对比两组患者的临床疗效、症状消失时间以及不良反应。结果观察组总有效率为96.05%,对照组总有效率为80.52%,两组患者临床疗效相比,差异有统计学意义(P<0.01);观察组咽部干燥灼热、声音嘶哑和食欲不振消失时间分别为(3.5±0.2)、(3.4±0.5)和(3.9±1.0)d,对照组咽部干燥灼热、声音嘶哑和食欲不振消失时间分别为(5.6±1.3)、(6.3±1.8)和(5.4±1.5)d,两组临床症状消失时间相比,差异均具有统计学意义(P<0.01);观察组不良反应发生率为7.89%,咽扁冲剂组不良反应发生率为10.39%,组间相比差异无统计学意义(P>0.05)。结论采用开喉剑喷雾剂治疗儿童急性咽喉炎的临床疗效显著,症状消失时间明显缩短,不良反应较少,值得推广。
Objective To explore the efficacy and safety of Kaihoujian sprays in the treatment for children with acute laryngitis.Methods A total of 160 patients with acute pharyngitis,who visited our hospital from May 2014 to January 2015,were divided into Experimental Group and Control Group according random number table,80 cases in each group. Cases in the Experimental Group were treated with Kaihoujian sprays,and patients in Control Group were treated with Pharyngeal flat granule. The clinical efficacy,the symptoms disappear time and adverse reactions of the two groups of patients were compared. Results The total effective rate of Experimental Group was 96. 05%,the total effective rate of Control Group was 80. 52%. The clinical efficacy in Experimental Group were significantly better than Control Group（ P 〈0. 01）. The length of time which the symptoms of throat dry or burning,hoarseness and loss of appetite disappeared in Experimental Group decreased significantly compared with Control Group（ P 〈0. 01）. The adverse reaction rate of Experimental Group was 7. 89%,and 10. 39% in Control Group. Conclusion Kaihoujian sprays can effectively improve the symptoms in children with acute laryngitis,and the safety was good.
出处
《临床军医杂志》
CAS
2015年第6期610-612,共3页
Clinical Journal of Medical Officers
