摘要
库欣综合征是高皮质醇血症所致的临床症候群,该病患者常合并高凝状态,其动静脉血栓事件、心血管病发生率乃至病死率均高于普通人群。本文将介绍库欣综合征高凝状态的病理生理机制,并对临床上预防性使用抗凝药物提供指导。
Cushing＇s syndrome（ CS） results from chronic exposure to excessive levels of glucocorticoids. Generally it is accompanied by a hypercoagulable state. Patients with CS have a higher risk of arterial and venous thrombotic events,cardiovascular disease morbidity and mortality. This review aims to introduce its pathophysiological mechanisms,and to provide examples and guidelines for antithrombotic prophylaxis in CS.
出处
《基础医学与临床》
CSCD
2016年第1期121-124,共4页
Basic and Clinical Medicine
基金
首都临床特色应用研究(Z151100004015099)
关键词
库欣综合征
高凝状态
静脉血栓栓塞症
Cushing＇s syndrome
hypercoagulable state
venous thromboembolism
