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内皮素-1在3种皮肤恶性肿瘤中的表达 被引量:1

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摘要 内皮素(endothelin,ET)是人体内一种强血管收缩剂,广泛表达于人体组织,皮肤中主要表达1型内皮素,即ET-1~[1]。人表皮角质形成细胞在紫外线照射下能合成和分泌出不同浓度的ET-1,并与黑素细胞胞膜上具有高亲和性的相应受体结合从而促进黑素细胞增殖并提高酪氨酸酶活性,从而使黑素的合成增加~[2-4]。这个机制与许多紫外线相关疾病有关,
出处 《临床皮肤科杂志》 CAS CSCD 北大核心 2016年第1期26-28,共3页 Journal of Clinical Dermatology
基金 泉州市财政科技局科技计划基金(2013Z70)资助项目
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参考文献9

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二级参考文献28

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