摘要
目的回顾性分析慢性心力衰竭合并慢阻肺患者治疗前后血清超敏C反应蛋白(hs-CRP)、肌酸激酶同工酶(CK-MB)和肌钙蛋白T(cTnT)的动态变化情况,以指导临床治疗。方法选择2012年11月-2014年12月于重庆市某医院内科就诊的单纯慢性心力衰竭患者及合并慢阻肺的心力衰竭患者各35例,收集人口学资料和治疗前后的hs-CRP,CK-MB和cTnT数值,进行横向和纵向综合比较。结果心力衰竭合并慢阻肺患者治疗前cTnT和hs-CRP水平均较高,分别为0.949ng/dL和278.0mg/L,与单纯心力衰竭患者比较,差异均有统计学意义(P<0.05)。治疗前2组患者CK-MB水平无明显差异;治疗后2组患者3项指标水平均较治疗前显著降低,但组间比较差异无统计学意义。结论合并慢阻肺的心力衰竭患者的治疗时间延长,多项指标综合评估患者病情更有临床意义和指导价值。
Objective To put forward clinical treatment suggestions by conducting retrospective study of dy- namic changes of CRP,CK-MB and cTnT before and after treatment in patients with chronic heart failure and chronic obstructive pulmonary disease. Methods The study was carried out in 35 patients with chronic heart failure and in 35 patients with both chronic heart failure and chronic obstructive pulmonary disease from Octo- ber 2012 to September 2014 in Chongqing Yimin Hospital. Demographics were collected. Crosswise compari- son was made to analyze dynamic changes of CRP, CK-MB and cTnT before and after treatment. Results The average indexes of cTnT （0.949 ng/dL） and hs-CRP （278 mg/L） were relatively higher before treatment in patients with both chronic heart failure and chronic obstructive pulmonary disease. Compared with patients Gn- ly with chronic heart failure, the difference is statistically significant（P〈0.05）. No obvious difference existed when comparing CK-MB among two groups before treatment. These 3 indexes declined after treatment for both groups without statistically significant difference. Conclusion More curative time is needed in patients with both chronic heart failure and chronic obstructive pulmonary disease. Multi-indexes assessment is of high- er clinical significance.
出处
《保健医学研究与实践》
2015年第6期40-42,共3页
Health Medicine Research and Practice
