摘要
目的应用二维斑点追踪显像（2D-STT）技术评价急性心肌缺血早期左房节段功能，探讨该技术评价急性心肌缺血早期左房节段功能的可行性。方法健康新西兰兔48只，开胸行左冠状动脉前降支（LAD）结扎术建立急性心肌缺血模型；分别在术前及术后10分钟采集心尖两腔、三腔、四腔切面动态二维图像；应用2D—STI技术评价左房15个节段在长轴方向的应变率（SR），分别比较心室收缩期（SR—S）、心室舒张早期（SR—E）、心室舒张晚期（SR—A）左房各节段应变率在术前、术后的差异。结果①左房辅泵功能指标：房顶部后壁、下壁、间隔，基底段间隔、下壁SR—A较术前降低（P〈0．01）；②左房储器功能指标：基底段下壁、前壁、间隔、侧壁，中间段下壁、前壁、间隔、侧壁，房顶部下壁SR—S均较术前降低（P〈0．01）；③左房通道功能指标：除基底段侧壁外，各节段SR—E均较术前降低（P〈0．01）。结论在急性心肌缺血早期，左房通道功能普遍受损，储器功能及辅泵功能部分受损，2D—STI技术评价忽}生心肌缺血早期左房节段功能是可行的。
Objective Apply 2 D - STI technique to evaluate the change of left atrial（ LA） segmental function in the early stage of acute myocardial ischemia,in order to investigate the feasibility of this technique to evaluate the segmental function of the LA in the early stage of acute myocardial ischemia. Methods Forty- eight healthy New Zealand rabbits were opened chest to es- tablish acute myocardial ischemia model by ligating the left anterior descending coronary artery. Dynamic two- dimensional image of apical two - chamber, three - chamber and four - chamber view were acquired pre - operation and 10 minutes pest - operadon.Apply 2D- STI technique to evaluate the strain rate（SR）of left atrial 15 segments in the direction of the long axis,compare the SR of each segment during ventricular systolic （SR- S ）, ventricular early diastolic （SR - E）and ventricular late diastolic（SR - A） between preoperative and postoperative respectively. Results （1）The parameter of LA pump function： the SR- A in the posterior,inferior and atrial septal of the room at the top,the atrial septal and the inferior of the basal segment were decreased post- op- eratian（ P 〈 0.01 ） ;（2）The parameter of LA reservoir function：the SR- S in the inferior of the basal segment,middle segment and room at the top, the anterior of the basal segment,middle segment, the atrial septal of the base segment,middle segment and the lat- eral of the base segment,middle segment were decreased post-operation（ P 〈 0.01 ）;（3） The parameter of LA conduit function： except the base segment of the lateral, the SR - E in each segment of left atrial were decreased post - operation（ P 〈 0.01 ） .Conclusion in the early stage of acute myocardial ischemia, the conduit function of left atrial was significantly impaired, the reservoir function and pump function were impaired pardaUy,it is feasible to apply the 2D- STI technique to evaluate the LA segmental function in the early stage of acute myocardial ischemia.
出处
《常州实用医学》
2015年第6期351-354,共4页
CHANGZHOU PRACTICAL MEDICINE
关键词
斑点追踪显像
急性心肌缺血
兔
左房
节段
应变率
Speckle tracking imaging
Acute myocardial ischemia
Rabbits
Left atrial
Segment
Strain rate
