期刊文献+

依那普利叶酸片联合知信行模式健康教育治疗H型高血压100例 被引量:1

下载PDF
导出
摘要 目的探讨知信行模式健康教育联合依那普利叶酸片对高同型半胱氨酸型高血压(简称H型高血压)患者的临床疗效及安全性。方法选取医院收治的H型2级高血压患者200例,随机分为观察组和对照组,各100例。对照组患者采用依那普利叶酸片进行治疗,观察组患者在对照组基础上加用知信行模式健康教育。结果观察组共95例患者完成研究,对照组共93例患者完成研究。观察组治疗后收缩压、舒张压较治疗前和对照组患者治疗后明显降低(P〈0.01);观察组患者靶器官损害发生率为2.11%,明显低于对照组的12.90%(χ~2=6.46,P〈0.05);观察组患者药品不良反应发生率为2.10%,与对照组患者的3.22%相比,差异无统计学意义(χ~2〈0.01,P=0.98)。结论知信行健康教育模式联合依那普利叶酸片治疗高血压可显著降低患者血压,提高患者高血压控制达标率,减轻靶器官损害,同时无明显不良反应,值得临床推广。
作者 侯文梅
出处 《中国药业》 CAS 2015年第23期242-244,共3页 China Pharmaceuticals
  • 相关文献

参考文献8

二级参考文献26

  • 1顾东风,Jiang He,吴锡桂,段秀芳,姚崇华,王家良,Kristi Reynolds,Chung-Shiuan Chen,Michael J.Klag,Paul K.Whelton.中国成年人主要死亡原因及其危险因素[J].中国慢性病预防与控制,2006,14(3):149-154. 被引量:75
  • 2GRAHAM IM, DALY LE,REFSUM HM,et al. Plasma homocysteine as a risk factor for vascular disease. The European Concerted Action Project[J]. JAMA ,1997,277(22) :1775 - 1781. 被引量:1
  • 3Homocysteine Lowering Trialists'Collaboration. Dose-dependent effects of folic acid on blood concentrations of homocysteine: a meta-analysis of the randomized trials [ J ]. Am J Clin Nutr, 2005,82(4) :806 - 812. 被引量:1
  • 4MAO G, HONG X, XING H,et al. Efficacy of folic acid and enalapril combined therapy on reduction of blood pressure and plasma glucose: a multicenter, randomized, double-blind, parallelcontrolled, clinical trial [ J ]. Nutrition, 2008,24 ( 11 - 12 ) : 1088 - 1096. 被引量:1
  • 5MARK SD, WANG W, FRAUMENI JF JR, et al. Lowered risks of hypertension and cerebrovascular disease after vitamin/mineral supplementation: the Linxian nutrition intervention [ J ]. Am J Epidemiol, 1996,143 (7) :658 - 664. 被引量:1
  • 6LONN E, YUSUF S, ARNOLD MJ,et al. Heart Outcomes Prevention Evaluation(HOPE) 2 Investigators[ J]. N Engl J Med, 2006,354 ( 15 ) : 1567 - 1577. 被引量:1
  • 7SAPOSNIK G, RAY JG, SHERIDAN P, et al. Homocysteinelowering therapy and stroke risk, severity, and disability: additional findings from the HOPE 2 trial[ J]. Stroke, 2009,40(4) : 1365 - 1372. 被引量:1
  • 8WANG X, QIN X, DEMIRTAS H, et al. Efficacy of folic acid supplementation in stroke prevention: a metaanalysis[ J]. Lancet, 2007,369(9576) : 1876 - 1882. 被引量:1
  • 9The European Stroke Organisation (ESO) Executive Committee and the ESO Writing Committee. Guidelines for management of ischaemic stroke and transient ischaemic attack 2008 [ J]. Cerebrovasc Dis ,2008,25 ( 5 ) :457 - 507. 被引量:1
  • 10ALBERT CM, COOK NR, GAZIANO JM, et al. Effect of folic acid and B vitamins on risk of cardiovascular events and total mortality among women at high risk for cardiovascular disease: a randomized trial[ J ]. JAMA, 2008,299 ( 17 ) :2027 - 2036. 被引量:1

共引文献2253

同被引文献6

引证文献1

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部