摘要
目的研究综合重症监护病房(ICU)患者肺部感染肠杆菌的耐药性特点,探索防控措施。方法采用回顾性调查方法,对某医院综合ICU住院病人肺部感染患者送检标本中肠杆菌科病原菌检测结果进行分析与评价。结果从该医院综合ICU住院病人肺部感染患者痰标本中共分离出肠杆菌科病原菌1 678株,主要是大肠埃希菌和肺炎克雷伯菌,构成比分别为56.38%和28.96%。痰标本分离的肠杆菌科病原菌对碳青霉烯类抗菌药物中的亚胺培南已经出现耐药菌株,但总敏感率仍然达到90%以上。肺部感染的肠杆菌科病原菌对多数抗菌药物普遍耐药。结论该综合ICU患者肺部感染肠杆菌科主要是大肠埃希菌和肺炎克雷伯菌,其对碳氢酶烯类已经出现耐药,应加强耐药菌监测和药敏试验,严格控制抗菌药物的应用。
Objective To study the characteristics of drug resistance of the patients with pulmonary infection in ICU,and to explore the prevention and control measures. Methods Retrospective investigation method was used to analyze and to evaluate the detection results of specimens of Enterobacteriaceae pathogen in a comprehensive hospital ICU from hospitalized patients with lung infection. Results 1 678 strains of Escherichia coli and Klebsiella pneumoniae were isolated from the sputum samples of the ICU hospitalized patients with pulmonary infection,which were 56. 38% and 28. 96% respectively. In Enterobacteriaceae pathogens isolated from sputum specimens the resistant strains against Carbapenems vinyl antimicrobial drug Imipenem had appeared,but the total susceptibility rate still reached more than 90%. The pathogenic bacteria in the lung infection were generally resistant to the majority of antimicrobial agents. Conclusion The main pathogens of pulmonary infection in the patients with ICU are Escherichia coli and Klebsiella pneumoniae,which are resistant to Hydrocarbon. So the the monitoring and drug sensitivity test should be strengthened.
出处
《中国消毒学杂志》
CAS
北大核心
2015年第12期1226-1229,共4页
Chinese Journal of Disinfection
关键词
重症监护病房
肺部感染
肠杆菌科
耐药性
防控措施
ICU
pulmonary infection
intestinal bacilli
drug resistance
preventive and control measures
