摘要
目的探讨氯吡格雷联合阿司匹林治疗急性心肌梗死(AMI)的临床效果。方法将2013年3月至2014年8月收治的70例AMI患者分为观察组(35例)和对照组(35例)。观察组在常规治疗基础上加用氯吡格雷联合阿司匹林治疗,对照组在常规治疗基础上加用氯吡格雷治疗。比较两组患者的临床疗效、冠状动脉再通率、再通时间、左心室射血分数(LVEF)、再闭塞率、血小板聚集率(PAR)。结果观察组患者临床疗效、冠状动脉再闭塞发生率、心血管事件发生率及治疗后LVEF和PAR均显著优于对照组(P<0.05),但是两组患者的冠状动脉再通率、再通时间差异无统计学意义(P>0.05)。结论氯吡格雷联合阿司匹林治疗急性心肌梗死疗效良好,值得临床推广。
Objective To observe the efficacy of clopidogrel combined with aspirin in acute myocardial infarction（AMI）.Methods A total of 70 AMI patients from February 2013 to May 2014 were divided into observation group（35 cases）and control group（35 cases）.Patients in the observation group received clopidogrel combined with aspirin in addition to regular therapy for AMI,while patients in the control group only received aspirin besides regular therapy for AMI.Clinical efficacy,coronary artery recanalization rate,recanalization time,left ventricular ejection fraction（LVEF）,coronary artery reocclusion rate,platelet aggregation rate（PAR）and rate of cardiovascular events were compared between these two groups.ResultsThe clinical efficacy,coronary artery reocclusion rate,rate of cardiovascular events,LVEF and PAR in the treatment group were significantly improved than those in the control group（P〈0.05）.However,there were no significant differences in the coronary artery recanalization rate,between these two groups（P〈0.05）.Conclusion Treatment of clopidogrel combined with aspirin in AMI can improve the clinical efficacy.
出处
《内蒙古医学杂志》
2015年第8期900-902,共3页
Inner Mongolia Medical Journal
