摘要
目的:探讨甲真菌病采用阿莫罗芬甲搽剂与伊曲康唑口服联合治疗和与特比萘芬口服联合治疗效果展开对比。方法:选取甲真菌病100例,随机分组,分别为阿莫罗芬甲搽剂与伊曲康唑联用组(A组,n=50)和特比萘芬口服联用组(B组,n=50),研究两组效果对比。结果:A组近期痊愈率为26%,远期痊愈率为86%;B组近期痊愈率为24%,远期痊愈率为60%,远期痊愈率比较,差异有统计学意义(P<0.05);A组真菌清除率为86%,B组为70%。两组均无严重不良事件发生。结论:甲真菌病采用阿莫罗芬甲搽剂与伊曲康唑口服联用,可获得理想的临床效果,真菌清除率较高,具有非常重要的应用价值,可显著改善患者生存质量。
Objective To study the onychomycosis by amor Luo Fenjia liniment and combination treatment with oral itraconazole and associated with oral terbinafine treatment effect comparison. Method The 100 cases of onychomycosis were selected and randomly divided into amor Luo Fenjia liniment and itraconazole together group（group A,n = 50）and amor Luo Fenjia liniment and oral terbinafine combi-nation group（group B,n = 50）. The effect of the two groups were compared. Results The recent recovery rate of group A was 26% ,the long - term cure rate was 86% ;the recent recovery rate of group B was 24% ,long - term recovery rate was 60% ,the long - term recovery rate of the two groups was statistically significant（P ﹤ 0. 05）;The fungal clearance rate of group A was 86% ,B group was 70% . Two groups had no serious adverse events. Conclusion Onychomycosis by amor Luo Fenjia liniment and oral itraconazole together,which can ob-tain ideal clinical effect,fungal clearance rate is higher,it has very important application value,can significantly improve the patients quality of life.
出处
《吉林医学》
CAS
2015年第18期4043-4045,共3页
Jilin Medical Journal
