摘要
目的初步探讨消胀贴神阙穴贴敷治疗脓毒症胃肠功能障碍的疗效。方法将30例患者按随机数字表法分为治疗组14例与对照组16例。两组均予基础治疗,对照组在基础治疗上加予枸橼酸莫沙必利片口服或胃管注入,治疗组在基础治疗上加予消胀贴神阙穴贴敷。两组疗程均为7 d。结果治疗组治疗后72 h,总有效率为71.43%;治疗7 d后,总有效率为64.29%。对照组治疗后72 h总有效率为43.75%;治疗7 d后总有效率56.25%。治疗组与对照组治疗后急性生理与慢性健康评分Ⅱ(APACHEⅡ)分别为(17.10±4.80)分、(20.70±5.70)分,分别低于治疗前的(26.70±4.00)分、(26.60±5.40)分(P<0.05),两组比较,差异有统计学意义(P<0.05);治疗后治疗组肠鸣音次数为(1.80±1.20)次/min,高于对照组的(0.80±1.00)次/min(P<0.05);治疗组在治疗第7日时腹腔压、腹围较治疗前均有显著变化(P<0.05),与对照组比较,差异有统计学意义(P<0.05);治疗组在疗后第7日血清二胺氧化酶(DAO)较治疗前明显下降(P<0.05),与对照组比较,差异有统计学意义(P<0.05)。结论相对于喂服胃肠动力药物,使用消胀贴神阙穴贴敷更能有效地治疗脓毒症胃肠功能障碍。
Objective： To study on the effect of Shenque acupoint application with Xiaozhang paste in the treat- ment on sepsis with gastrointestinal dysfunction. Methods： 30 cases with the diagnosis of gastrointestinal dys- function in sepsis were randomly divided in the treatment group with 14 cases and the control group with 16 cas- es. Two groups were given basic treatment. In the control group,Mosapride tablets were given orally or injected into the tube on the basis of the basic therapy,while in the treatment group,Shenque acupoint application with Xiaozhang paste were used on the basis of the basic therapy. The treatment course lasted for 7 days. Results： In the treatment group,the total effective rate was 7t.43% after 72 hours of treatment,and 64.29% after 7 days of treatment. The data were 43.75% and 56.25% the in control group respectively. The effective rate of the treatment group was higher than that of the control group （P〈 0.05）. APACHE l] score of the treatment group after treatment was （17.1±4.8）,lower than （26.7±4.0） before treatment. It was the same for the control group, （20.7±5.7） after treatment and（26.6±5.4） before treatment. The difference of APACHE Ⅱ score between before and after treatment was statistically significant in comparison between groups （P 〈 0.05）. After treatment,the bowel soundsof the treatment group was （ 1.8_＋ 1.2 ）/per minute, the control group （0.8_＋ 1.0）/per minute, with statistical significance （ P 〈 0.05）. For the intra-abdominal pressure, abdominal circumference and serum DAO in the treatment group,the difference was statistically significant in comparison within groups. And there were no statistically significant dif- ferences in the control group. Conclusion： Compared with gastrointestinal drug,Xiaozhang paste can be more ef- fective in the treatment on sepsis with gastrointestinal dysfunction.
出处
《中国中医急症》
2015年第12期2116-2119,共4页
Journal of Emergency in Traditional Chinese Medicine
基金
中国中医科学院基本科研业务费自主选题项目(ZZ070844)
关键词
脓毒症
胃肠功能障碍
消胀贴
神阙穴
Sepsis
Gastrointestinal dysfunction
Xiaozhang paste
Shenque acupoint
