摘要
近年来药物载体材料的研究已成为医学领域研究的热点。选择适宜的载体材料是获得良好给药系统的关键。丝素蛋白是一种天然蛋白质,具有良好的生物相容性和机械性能,可生物降解,无毒,易于加工制备,因而是一种优良的药物载体材料。本文基于丝素蛋白的结构和特点,综述了它作为药物载体材料的最新研究进展。
Recently, drug delivery materials have become the hotspot of medical study. Suitable delivery material plays an important role in constructing an excellent drug delivery system. Silk fibroin is a naturally occurring protein polymer with excellent biocompatibility, remarkable mechanical properties, biodegradability and outstanding proces- sability. Due to its unique properties, silk fibroin has become a favorable carrier material for the incorporation and delivery of a range of therapeutic agents. Based on the structure and characteristics of silk fibroin, this article pro vides an overview of the recent research progress of silk fibroin used as drug delivery materials.
出处
《生物医学工程学杂志》
EI
CAS
CSCD
北大核心
2015年第6期1364-1368,共5页
Journal of Biomedical Engineering
基金
国家自然科学基金资助项目(51303124)
山西省自然科学基金资助项目(2013011012-2)
纤维材料改性国家重点实验室开放课题项目资助(V201106)
关键词
丝素蛋白
药物释放
载体
silk fibroin
drug release
carrier
