摘要
笔者诊治1例64岁男性肝内胆管细胞癌（ICC）患者。本患者主要表现为腹痛、高热和肝脏多发占位，曾被诊断为急性胆囊炎、肝脏转移瘤，抗感染治疗后发热仍难以控制，查糖类抗原199（CA199）3222U/ml，结合肝穿刺活检明确诊断为ICC，肿瘤坏死伴感染，急性胆囊炎，给予姑息、对症治疗，2个月后死亡。根据文献报道和笔者的临床经验，ICC早期发现难，恶性程度高，可伴发坏死感染，根治性切除机会少，预后差。老年消化科医师应熟悉ICC特点，重视健康查体工作，以利于本病的早期诊断和治疗。
We reported a 64-year-old male with intrahepatic cholangiocarcinoma （ICC）, whose main manifestations were abdominal pain, fever and multiple hepatic masses. He was once diagnosed with acute cholecystitis and hepatic metastatic carcinoma. After anti-infective therapy, his fever was still difficult to control. The serum level ofcarbohydrate antigen 199 （CA199） was as high as 3222U/ml, and ultimately, he was diagnosed withICC and neoplasm necrosis accompanied with infection and acute cholecystitis after liver puncture biopsy.The patient wasgiven palliative and symptomatic treatment, and diedin 2 months later. Based on literature and our clinical experience, it is difficultto diagnoseICCatearly period. It has highmalignancy, may be accompanied with necrosis and infection sometimes, has few opportunities for radical excision, and thus, poor prognosis finally. In order to facilitate the early diagnosis andtreatmentof this disease, geriatric gastroenterology physicians should be familiar with the characteristics ofICC, and pay more attention tohealth examination.
出处
《中华老年多器官疾病杂志》
2015年第11期868-872,共5页
Chinese Journal of Multiple Organ Diseases in the Elderly
关键词
肝内胆管细胞癌
感染
诊断
intrahepatic cholangiocarcinoma
infection
diagnosis
