摘要
目的分别采用西医和中西医结合两种治疗方法对功能性消化不良(functional dyspepsia,FD)患者进行治疗。对比两种治疗方法对FD患者的临床症状和生活质量的影响,分析中西医结合疗法对FD患者的综合治疗作用,探讨该治疗方法的临床适用性。方法采用随机数字表法,将符合纳入标准的60例FD患者分为两组,西医治疗组30例,釆用西药治疗;中西医结合治疗组30例,釆用中医辨证论治加西药治疗。临床研究中选择疗程28d及治疗后6个月两组患者的中医FD症状量表积分及SF-36健康调查量表(short-form-36 health survey,SF-36)积分进行比较,综合分析两组治疗效果。结果 1两组治疗28d,总有效率西医治疗组73.33%,中西医结合治疗组86.67%,两组对比有明显差异(P<0.05),中西医结合治疗组临床疗效较西医治疗组好;2治疗28d,比较两组患者SF-36健康调查量表积分,西医治疗组积分(447.37±43.307),中西医结合治疗组积分(493.63±96.204),两组对比(P<0.05),中西医结合治疗组的生活质量改善优于西医治疗组。3治疗后6个月,总有效率西医治疗组56.67%,中西医结合治疗组76.67%,两组对比(P<0.05)有明显差异,中西医结合治疗组长期疗效较西医治疗组好;4治疗后6个月,比较两组患者SF-36健康调查量表积分,西医治疗组积分(441.53±46.953),中西医结合治疗组积分(518.57±55.069),两组对比(P<0.05),中西医结合治疗组的长期生活质量改善优于西医治疗组;5治疗后6个月,比较两组复发率,西医治疗组23.73%,中西医结合治疗组11.54%,两组对比(P<0.05)有明显差异,西医治疗组复发率高于中西医结合治疗组。结论 1中西医结合治疗能有效改善FD患者的临床症状和生活质量,整体疗效优于单纯西药治疗,复发率小,长期疗效好。2本研究中所采用中西医结合辨证治疗FD的方法,体现了病证结合标本兼治的临床诊疗思维,值得临床医师进一步研究和探讨。
Objective Using the methods of both the Western medicine and the integrated medicine to treat functional dyspepsia （FD） , to compare the effect of the two kinds of treatment programs on the clinical syndrome and the quality of life （QOL） , to analyze the synthetical treatment of integrated medicine on FD, and to discuss the clinical application of therapy of integrated medicine. Methods Selecting 60 cases of patients which were confirmed FD. All the patients were assigned into two groups by using the method of random number table. The Western medicine （WM） treatment group included 30 cases, which applied conventional modern medicine treatment. 30 cases in the integrated medicine （IM） treatment group which adopt the treatment based on syndrome differentiation and Western medicine. The course of treatment was 28 days. Six months later, the objective indicators on the total scores of both the symptoms of FD and SF-36 （ short-form-36 health survey, SF-36） from the patients of two groups were extracted to contrast. The therapeutic effect of the two groups was analyzed. Results After being treated 28 days, the total effective rate of the WM treatment group and the IM treatment group was 73.33% and 86.67% , respectively, and there was significant （P 〈0.05）. The IM treatment group was superior to the WM treatment group in improving the symptoms of FD. After being treated 28 days , the total scores of SF-36 of the WM treatment group and the IM treatment group was 447.37 ±43. 307 and 493.63 ± 96. 204, respectively （P 〈 0.05 ）. The IM treatment group was superior to the WM treatment group in improving the QOL. Six months later, the total effective rate of the WM treatment group and the IM treatment group was 56.67% and 76.67%, respectively （P 〈0.05）. The long-term therapeutic effect of the IM treatment group was better than that of the WM treatment group in improving the symptoms of FD. Six months later , the total scores of SF-36 of the WM treatment group and the IM treatment group w
出处
《光明中医》
2015年第12期2564-2568,共5页
GUANGMING JOURNAL OF CHINESE MEDICINE
关键词
功能性消化不良
中西医结合治疗
临床疗效
生活质量
Functional dyspepsia
Therapy of integrated medicine
Clinical therapeutic effect
Quality of life
