摘要
目的研究中青年与老年患者急性sT段抬高心肌梗死（STEMI）冠状动脉内自发性再通的临床特点。方法连续入选2013-01～2015-07南京市第一医院108例急性STEMI冠状动脉内自发性再通的患者，记录患者的人口学资料、临床基线数据、冠状动脉造影结果及院内生存率。根据年龄分为两组，一组为中青年组，另外一组为老年组。比较两组人群的临床特点及院内生存率差别。结果与老年组患者比较，中青年组急性STEMI患者在性别构成比、持续胸痛时间、有无胸痛症状、心肌梗死部位、硝酸甘油含服史、吸烟史、高血压病史、是否累及主干、院内生存率、住院心力衰竭发生率、梗死前心绞痛、心肌梗死并发症、心源性休克、冠状动脉闭塞部位及是否需要血管活性药物等指标方面差异无统计学意义（P〉0．05）。在首发冠心病方面，中青年组较老年组具有更高的发生比率（P〈0．05）。在阿司匹林服用史、高脂血症史、他汀药物服用病史、既往PCI病史等方面，老年组发生比率高于中青年组，差异有统计学意义（P〈0．05）。结论中青年与老年急性STEMI冠状动脉内自发性再通患者在人口学资料、临床基线数据、冠状动脉造影结果及院内生存率等方面差异无统计学意义（P〉0．05）；在首发冠心病比率上中青年组要高于老年组；在阿司匹林服用史、高脂血症史、他汀药物服用病史、既往PCI病史等方面老年组具有较高的发生率。
Objective To explore the clinical features of the patients with acute ST segment elevation myocardial infarction who got a spontaneous reperfusion between middle age and the elderly patients. Methods Sixty - eight acute ST segment elevation myocardial infarction （STEMI） patients with spontaneously recanalization in the coronary artery were consecutively enrolled. The patients were divided into two groups based on age, middle age group and elderly age group. The demographic data, clinical baseline data, coronary angiographic findings and hospital survival rate were documented in the two groups. Results Between the two groups, gender composition ratio, chest pain lasting time, ＂with or without chest pain symptoms＂, myocardial infarction site, nitroglycerin containing history, smoking history, aspirin taking history, hyperlipidemia history, hypertension history, statin - taking history, PCI history, whether involving the trunk, in - hospital survival rate, heart failure rate, pre - infarction angina, myocardial infarction complication, cardiogenic shock, coronary occlusion site, ＂whether to need to vasoactive drugs＂ were counted and analyzed with no significant difference （ P 〉 0. 05 ）. However, the middle group had a higher rate of initial coronary heart disease （P 〈 0. 05 ）. ConclusionThere is no significant difference between middle and elderly patients with STEMI in the demographic data, baseline clinical data, coronary angiography results and hospital survival rate. The middle age group has a higher rate of initial coronary heart disease, which suggests that first time - STEMI in middle age people is prone to spontaneous reperfusion.
出处
《中国急救医学》
CAS
CSCD
北大核心
2015年第12期1100-1102,共3页
Chinese Journal of Critical Care Medicine
基金
南京市卫生青年人才培养项目（QRX11246）
南京市科委面上项目（201402047）
