摘要
基质金属蛋白酶-2(matrix metalloproteinase-2,MMP-2)是一种能够降解细胞外基质(extracellular matrix,ECM)成分的肽链内切酶,广泛参与血管形成、炎症反应和损伤修复等一系列的病理生理过程。本文综述了MMP-2的生物学特性以及在心脑血管疾病、损伤中的作用和应用价值,为法医学检案工作提供参考资料。
Matrix metalloproteinase-2 （MMP-2） is an endopeptidase which is capable of degrading a wide range of components of the extracellular matrix and widely participates in the pathophysiological processes of angiogenesis, inflammation and wound healing. Advanced study on biological characteristic of MMP-2 and its role and applicable value in forensic medicine are reviewed in this article, which may provide reference for practical work.
出处
《中国法医学杂志》
CSCD
2015年第6期590-593,共4页
Chinese Journal of Forensic Medicine
基金
国家自然科学基金青年科学基金项目(81202383)
