摘要
目的研究胎儿f FN和宫颈长度联合监测对先兆早产孕妇最终发生早产的预测价值。方法择取2012年12月-2014年11月在我院就诊的、患有先兆早产的孕妇106例,取其阴道分泌物制成标本测定f FN,同时借助超声手段探明子宫颈长度,分析联合使用两种方法预测早产的敏感性、特异性。结果 f FN呈现阳性结果且宫颈长度不超过3 cm的患者共有36例,f FN呈现阳性结果且宫颈长度为3 cm及以上的患者共有4例。f FN呈现阴性结果且宫颈长度在3 cm及以上患者有56例,f FN呈现阴性结果且宫颈长度在3 cm以下的患者有10例,f FN呈现阳性结果且宫颈长度不超过3 cm的36例患者在1、2、3周内的分娩率依次是88.89%、91.67%、100.00%;f FN呈现阴性且宫颈长度在3 cm及以上的患者均未出现早产。借助f FN和宫颈长度对早产三周进行联合预测,其敏感性与特异性、阳性与阴性的预测值均为100.00%。结论监测孕妇的f FN含量可以于一定程度上预测早产,若联合超声检测宫颈长度,则可以使孕妇先兆早产的检出率与预测率大大提高。
【Objective】To study the predictive value of fetal f FN and cervical length combined with monitoring the premature delivery of threatened premature pregnancy.【Methods】 chooses the December 2012 to 2014 November during the past two years in our hospital, with 106 cases of pregnant women with threatened preterm labor, taken vaginal secretion specimens made of FFN determination, at the same time with the ultrasonic technique proved cervical length, conjoint analysis using two methods predict premature sensitivity, specificity. 【Results】 there were 36 cases of f FN presenting positive results and cervical length no more than 3 cm, f FN showed positive results and cervical length was 3 cm and more than 4 cases. FFN showed negative results and cervical length in 3 cm or more patients with 56 cases, FFN showed negative results and cervical length in patients less than 3 cm with 10 cases of.FFN showed positive results and cervical length not more than 3 cm in 36 patients in one, two, three weeks of delivery rate in turn is 88.89%, 91.67% and 100.00%; FFN negative presentation and cervical length in 3 cm and above patients did not appear premature. The sensitivity and specificity of the combination of f FN and cervical length for three weeks of preterm delivery were predicted, and the predictive values of both positive and negative were 100%. 【Conclusion】 monitoring the content of f FN in pregnant women can predict the premature delivery, and the detection rate and the prediction rate of the threatened premature delivery can be greatly improved by the combination of ultrasound and detection of cervix length.
出处
《中国医学工程》
2015年第11期15-16,共2页
China Medical Engineering
关键词
胎儿纤维链接蛋白
超声检查
子宫颈长度
早产预测
fetal fibrous link protein
ultrasound examination
cervix length
premature forecast
