摘要
目的:探讨适形放射治疗联合参一胶囊在Ⅲ期非小细胞肺癌治疗中的临床疗效。方法:选取本院自2011年4月至2014年6月经病理及影像学资料明确证实的Ⅲ期非小细胞肺癌患者60例,随机分为两组,即对照组和治疗组。对照组行单纯适形放射治疗;治疗组在适形放射治疗的同时,给予口服参一胶囊8周。治疗期间观察患者有无乏力症状,定期行血液学检查,完成治疗后4周行胸部CT检查。结果:治疗组出现不同程度乏力的患者数明显少于对照组,差异显著,具有统计学意义(P<0.05);定期血常规检验,治疗组出现白细胞、血红蛋白减低的患者比率明显低于对照组,差异具有统计学意义(P<0.05);两组近期治疗效果相近,差异无统计学意义(P>0.05)。结论:放射治疗联合参一胶囊治疗可以改善患者乏力状况,降低放射治疗引起的血液不良反应的发生几率。
Objective： To investigate the clinical effects of the conformal radiation therapy combined with Shenyi capsule in the treatment of stage Ⅲ non-small-cell lung cancer （NSCLC）. Methods： The 60 patients of stage Ⅲ NSCLC who confirmed clearly by pathological and radiological data from April 2011 to June 2014 in our hospital were randomly divided into control group and treatment group. The control group was treated with conformal radiation therapy; and the treatment group was treated with the conformal radiation therapy and Shenyi capsule for 8 weeks. During the treatment, to observe patients have weak or not and to carry out regularly blood tests. Four weeks after therapy, to go for a chest CT inspection. Results： The weak patients in treatment group were significantly less than the control group with statistical significance（P〈0.05）; the percentage of patients who appeared the decrease of white cells and hemoglobin in the treatment group were significantly lower than the control group, and the difference had statistical siguificance（P〈0.05）; the short-term outcome of treatment of the two groups was approximate without statistical significance （P〉0.05）. Conclusion： Radiation therapy combined with Shenyi capsule can improve the weak status of patients and reduce blood undesirable reaction caused by radiotherapy.
出处
《现代生物医学进展》
CAS
2015年第34期6753-6755,6613,共4页
Progress in Modern Biomedicine
基金
国家自然科学基金项目(81101085)
关键词
适形放射治疗
参一胶囊
非小细胞肺癌
Conformal Radiation Therapy
Shenyi Capsule
Non-small-cell Lung Cancer （NSCLC）
