摘要
目的：探讨复方角菜酸醋栓对肛裂术后创面愈合的临床效果及安全性。方法：2011年6月~2014年6月肛裂术后患者88例随机分为观察组（n=44）和对照组（n=44）。对照组给予常规处理,观察组在对照组基础上加用复方角菜酸醋栓,疗程均为14d。比较两组创面平均愈合时间、肉芽生长时间及祛腐时间、疗效、术后疼痛程度评分及术后创面水肿评分、术后创面面积。结果：观察组治疗14 d后创面愈合时间、肉芽生长时间及祛腐时间均短于对照组（P〈0.05）;观察组总有效率为93.18%高于对照组的77.27%（P〈0.05）;观察组术后第7天、第14天疼痛评分和创面水肿评分低于对照组同期（P〈0.05）,创面面积小于对照组同期（P〈0.05）。结论：复方角菜酸醋栓外用对肛裂术后创面愈合的临床效果显著安全可靠。
Objective： To investigate the clinical efficacy and safety of compound carraghenates suppositories in the treatment of wounds after anal fissure operation. Methods： Eighty-eight cases of patients with anal fistula post-operation wounds were diagnosed from June 2011 to June 2014 and randomly divided into the observation group （n =44） and the control group （n =44）. The control group was treated with the conventional treatment and the observation group was treated with external compound carraghenates suppositories additionally. The efficacy, average healing time, growing time of granulation tissue and removal time of necrotic tissue, pain disappear- anee time and wound edema disappearance time after the operation and the area of wound surface in the two groups were observed and compared. Results. After the 14-day treatment, the time of wound healing, granulation growth and cure in the observation group was shorter than that in the control group （P 〈0.05）. In the observation group, the total effective rate （93.18%） was higher than that in the control group （77.27%, P 〈 0.05 ）. After the 7-day and 14-day treatment, the pain score and wound edema score in the observa- tion group were significantly lower than those in the control group （P 〈 0.05）, and the wound area was significantly smaller than that in the control group （P 〈 0.05 ）. Conclusion： The clinical efficacy of external compound carraghenates suppositories in the treatment of wounds after anal fissure operation is significant, safe and reliable.
出处
《中国药师》
CAS
2015年第12期2100-2101,2104,共3页
China Pharmacist
关键词
复方角菜酸酯栓
肛裂
创面
疗效
安全性
Compound carraghenates suppositories
Anal fissure
Efficacy
Safety
