摘要
目的探讨中青年脑梗死发病的相关因素.方法选择绍兴文理学院附属医院2010年1月-2014年10月35～45岁脑梗死住院患者105例为脑梗死组,同期体检且无神经症状的正常中青年110人为对照组,收集两组一般资料、实验室检测结果及颈动脉超声结果等资料,分析中青年脑梗死相关因素.结果多因素Logistic回归分析显示,高血压病史、糖尿病病史、脂代谢紊乱、吸烟史、肥胖、颈动脉斑块、高半胱氨酸血症和抗心磷脂抗体阳性是中青年脑梗死的独立危险因素,其OR值分别为14.614、5.129、44.970、26.180、45.196、258.786、14.585和5.145.结论高血压、糖尿病、脂代谢紊乱、吸烟、肥胖、颈动脉斑块、高半胱氨酸血症、抗心磷脂抗体阳性与中青年脑梗死发病密切相关,应积极预防与控制.
Objective To explore the risk factors of cerebral infarction in youth,and to provide evidence for prevention and control. Methods A total of 105 patients aged 35 -45 years old with cerebral infarction in the affiliated hospital of Shaoxing University from January 2010 to October 2014 were recruited as the cerebral infarction group . The healthy people without neurological symptoms were recruited as the control group. The two groups were compared for the risk factors of cerebral infarction in the youth. Results Logistic regression analysis showed that high blood pressure,diabetes,lipid disorders, smoking,obesity,unstable plaque,high homocysteine and anti - cardiolipin antibodies were the risk factors for cerebral infarction in the youth. The value of ORs and 95% CIs interval value for high blood pressure,diabetes,lipid disorders, smoking,obesity,unstable plaque,high homocysteine and anti - cardiolipin antibodies was 14. 614(0. 469 -47. 273),5. 129 (1. 541 -28. 466),44. 970(2. 789 -101. 549),26. 180(1. 085 - 51. 912),45. 196(2. 572 - 205. 674),258. 786(4. 892 -367. 678),14. 585(1. 770 - 49. 662)and 5. 145(1. 005 - 20. 293),respectively. Conclusion High blood pressure, diabetes,lipid disorders,smoking,obesity,unstable plaque,high homocysteine and anti - cardiolipin antibodies were closely related with cerebral infarction in the youth,and it is necessary to prevent and control the influencing factors and diseases.
出处
《浙江预防医学》
2015年第12期1206-1209,共4页
Zhejiang Journal of Preventive Medicine
基金
绍兴市科学技术局项目(2012B70071)
关键词
中青年
脑梗死
相关因素
Young and middle-age
Cerebral infarction
Influencing factors
