摘要
目的:对急性心肌梗死(AMI)后并发急性肾损伤(AKI)患者的临床特征进行分析并探讨并发急性肾损伤的危险因素。方法:回顾性分析148例AMI后并发AKI患者的临床资料并设为观察组,并选取50例单纯AMI患者的临床资料作为对照组进行比较,分析AMI并发AKI患者的临床特征及危险因素。结果:观察组患者病死率、年龄、高血压病史、糖尿病史、慢性肾脏疾病史发生率显著高于对照组(P<0.01,P<0.05),住院时间、病变血管数、发病至入院时间、Killip分级、左室射血分数以及N前端脑钠肽(NT-proBNP)水平差异有统计学意义(P<0.01,P<0.05)。多因素分析证实,高血压病史、慢性肾脏疾病史、发病至住院时间>6h、入院Killip分级>2级是发生AKI的危险因素。结论:AMI后并发AKI患者的病死率高,高血压病史、慢性肾脏疾病史、发病至住院时间>6h、入院Killip分级>2级是AKI发生的独立危险因素。
Objective：To study the clinical features and risk factors in patients with acute myocardial infarction（AMI）induced acute kidney injury（AKI）.Method：A total of 148 patients with AMI induced AKI were set as observation group and 50 patients with AMI were set as control group.The Clinical features and risk factors were studied by compare the clinical data between two groups.Result：The death rate,age,hypertension rate,diabetes rate,chronic kidney disease rate in observation group were significantly higher than those in control group（P〈0.01,P〈0.05）.The number of vascular lesions,in hospital time,Killip score,left ventricular ejection fraction（LVEF）,NT-proBNP level were significantly different between two groups（P〈0.01,P〈0.05）.According to Logistic analysis hypertension,chronic kidney disease,time from AMI attack to hospitalization〉6h,Killip score〉2were the risk factors of AMI induced acute kidney injury.Conclusion：AMI induced AKI has a high death rate and hypertension,chronic kidney disease,time from AMI attack to hospitalization 〉6h,Killip score〉2were the risk factors.
出处
《临床急诊杂志》
CAS
2015年第11期883-885,共3页
Journal of Clinical Emergency
基金
佛山市科技计划项目(No:2015140)
关键词
急性心肌梗死
急性肾损伤
临床特征
危险因素
acute myocardial infarction
acute kidney injury
clinical features
risk factors
