摘要
目的分析护理干预在高通量血液透析（HFHD）患者中的应用效果。方法选择2013年5月-2014年5月我院收治的64例慢性肾衰竭患者,按照随机数字表法将其分为研究组和对照组,各32例。所有患者均给予HFHD治疗,透析过程中对照组给予常规护理,研究组常规护理基础上给予综合护理干预,比较两组患者第1、3次透析后血清尿素氮（BUN）、肌酐（Cr）、β2微球蛋白（β2MG）及第1次和6个月透析后血清β2MG、白细胞介素-6（IL-6）的浓度,并比较两组患者透析过程中并发症发生率。结果两组患者第1、3次透析后血清BUN、Cr、β2MG差异无统计学意义（P〉0.05）;第1次透析后,研究组血清β2MG及IL-6浓度与对照组比较,差异无统计学意义（P〉0.05）;透析6个月后,研究组血清β2MG及IL-6浓度分别为（48.7±9.9）μmol/L、（10.0±3.2）ng/L,显著低于对照组的（58.0±7.1）μmol/L及（14.3±3.6）ng/L,差异有统计学意义（P〈0.05）;研究组患者在透析过程中并发症发生率为3.12%,显著低于对照组的18.75%,差异有统计学意义（P〈0.05）。结论护理干预在HFHD患者透析中起着关键性的作用,可减少透析并发症的发生。
Objective To analyze the Application effect of nursing intervention on patients with high flux hemodialysis（FHHD）. Methods 64 patients with MHD in our hospital from May 2013 to May 2014 were selected and divided into study group and control group according to the random number table method,with 32 cases in each group.All patients were treated with FHHD,the control group was given routine nursing,the study group was treated with comprehensive nursing intervention on the basis of routine nursing.The serum blood urea nitrogen（BUM）,creatinine（Cr）,beta-2micoglobulin（β2-MG） at 1,3 times of dialysis and the serum concentration of β2-MG,interleukin-6（IL-6） after the first time and 6 months later of dialysis in two groups were compared,and incidence of complications during dialysis was compared between two groups. Results The serum BUN,Cr,β2MG in two groups at 1,3 times of dialysis had no significant difference（P〈0.05）.The serum β2MG and IL-6 concentrations in study group after 1 time of dialysis,had no significant difference with the control group（P〈0.05）.After 6 months of dialysis,serum β2MG and IL-6 concentration in study group respectively were（48.7±9.9） μmol/L and（10.0±3.2） ng/L,which wrer significantly lower than（58.0 ±7.1） μmol/L and（14.3±3.6） ng/L of control group,with significant difference（P〈0.05）.The complication rate during dialysis in study group was 3.12%,which was significantly lower than 18.75% of control group,with significant difference（P〈0.05）. Conclusion Nursing intervention is an important factor in improving the dialysis adequacy of patients with FHHD,which can reduce dialysis complications.
出处
《中国当代医药》
2015年第33期175-177,180,共4页
China Modern Medicine
关键词
护理干预
高通量血液透析
血液净化
Nursing intervention
High flux hemodialysis
Blood purification
