期刊文献+

预测自发性脑出血短期临床结局的相关因素分析 被引量:5

Risk Factors of Short-term Clinical Outcome in Patients with Spontaneous Intracerebral Hemorrhage
下载PDF
导出
摘要 目的:对预测自发性脑出血短期预后的相关危险因素进行分析。方法:回顾性分析自发性脑出血患者的临床资料。将可能影响发病后30 d临床结局的危险因素进行单因素分析及多因素Logistic回归分析。结果:纳入自发性脑出血患者418例,其中结局良好组105例,结局不良组146例。年龄≥75岁(OR=2.57,P<0.01)、幕下来源血肿(OR=6.51,P<0.01)、血肿体积≥30 cm^3(OR=13.41,P<0.01)、收缩压≤110或≥200 mm Hg(OR=4.05,P<0.01)、血肿破入脑室(OR=4.01,P<0.01)、合并慢性疾病(OR=4.18,P<0.01)为自发性脑出血短期预后不良的独立危险因素。结论:明确自发性脑出血短期预后不良的相关因素可指导临床决策。 Objective:To identify risk factors which may be closely associated with short-term clinical outcomes in patients with spontameous intracerebral hemorrhage(SICH). Methods: A retrospective study with SICH patients was performed. Univariate analysis and multivariate logistic regression analysis were performed to determine the risk factors. Results: In all 418 patients with SICH were enrolled, including 105 cases in favorable outcome group and 146 cases in poor outcome group. Independent prognostic factors of 30-day poor outcome after SICH were, age≥75 years (OR=2.57, P〈0.01), comorbidities (OR=4.18, P〈0.01), systolic blood pressure ≤110 or ≥200 mmHg (OR=4.05, P〈0.01), presence of intraventricular hematoma (OR=4.01, P〈0.01), hematoma volume ≥30 cm^3 (OR=13.41, P〈0.01) and infratentorial hematoma (OR=6.51, P〈0.01). Conclusion: Factors analysis for prediction of short-term clinical outcome could help to stratify SICH patients with regard to short-term clinical outcome.
出处 《神经损伤与功能重建》 2015年第6期480-483,共4页 Neural Injury and Functional Reconstruction
关键词 脑出血 危险因素 结局 预后 多因素分析 intracerebral hemorrhage risk factors outcome prognosis Logistic regression analysis
  • 相关文献

参考文献2

二级参考文献20

  • 1Qureshi AI, Suri ME Ostrow PT, Kim SH, Ali Z, Shatla AA, et al. Apoptosis as a form of cell death in intracerebral hemorrhage. Neurosurgery 2003; 52: 1041-1048. 被引量:1
  • 2Mendelow AD, Gregson BA, Fernandes HM, Murray GD, Teasdale GM, Hope DT, et al. Early surgery versus initial conservative treatment in patients with spontaneous supratentorial intracerebral haematomas in the International Surgical Trial in Intracerebral Haemorrhage (STICH): a randomised trial. Lancet 2005; 365: 387-397. 被引量:1
  • 3Fujii Y, Takeuchi S, Sasaki O, Minakawa T, Tanaka R. Multivariate analysis of predictors of hematoma enlargement in spontaneous intracerebral hemorrhage. Stroke 1998; 29: 1160-1166. 被引量:1
  • 4Haschtmann D, Stoyanov JV, Gedet P, Ferguson SJ. Vertebral endplate trauma induces disc cell apoptosis and promotes organ degeneration in vitro. Eur Spine J 2008; 17: 289-299. 被引量:1
  • 5Mayer SA, Lignelli A, Fink ME, Kessler DB, Thomas CE, Swarup R, et al. Perilesional blood flow and edema formation in acute intracerebral hemorrhage: a SPECT study. Stroke 1998; 29: 1791-1798. 被引量:1
  • 6Nath FP, Jenkins A, Mendelow AD, Graham DI, Teasdale GM. Early hemodynamic changes in experimental intracerebral hemorrhage. J Neurosurg 1986; 65: 697-703. 被引量:1
  • 7Gong C, Boulis N, Qian J, Turner DE, Hoff JT, Keep RF. Intracerebral hemorrhage-induced neuronal death. Neurosurgery 2001; 48: 875-883. 被引量:1
  • 8Matsushita K, Meng W, Wang X, Asahi M, Asahi K, Moskowitz MA, et al. Evidence for apoptosis after intercerebral hemorrhage in rat striatum. J Cereb Blood Flow Metab 2000; 20: 396-404. 被引量:1
  • 9Felberg RA, Grotta JC, Shirzadi AL, Strong R, Narayana P, Hill-Felberg S J, et al. Cell death in experimental intracerebral hemorrhage: the "black hole" model of hemorrhagic damage. Ann Neurol 2002; 51: 517-524. 被引量:1
  • 10Han N, Ding S J, Wu T, Zhu YL. Correlation of free radical level and apoptosis after intracerebral hemorrhage in rats. Neurosci Bull 2008; 4: 351-358. 被引量:1

共引文献541

同被引文献42

引证文献5

二级引证文献30

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部