摘要
目的探讨早期肠内和肠外营养对结直肠癌患者术后恢复的影响。方法选取该院2012年12月—2014年12月收治的120例结直肠癌患者,分为肠内营养(Enteral nutrition,EN)组(40例)、肠外营养(Parenteral nutrition,PN)组(40例)和EN联合PN组(40例),分析比较各组患者营养指标、应激指标、免疫指标、术后并发症、胃肠道恢复时间、住院时间和治疗费用。结果 3组患者术后,在营养指标上,EN联合PN组中PA、ALB和TF值均高于EN组和PN组(P<0.05),在应激指标上,EN联合PN组中CRP值低于EN组和PN组(P<0.05),EN组中CRP值低于PN组(P<0.05);在免疫指标上,EN联合PN组中CD3、CD4和CD4/CD8百分比均高于EN组和PN组(P<0.05),EN组中CD3、CD4和CD4/CD8百分比均高于PN组(P<0.05);在术后并发症上,EN联合PN组术后并发症发生率为5.0%,要显著低于PiN组(20.0%)(P<0.05);在胃肠道恢复时间和住院时间上,EN联合PN组均短于EN组和PN组(P<0.05),EN组短于PN组(P<0.05);在治疗费用上,EN联合PN组少于EN组和PN组(P<0.05),EN组少于PN组(P<0.05)。结论在结直肠癌术后单纯EN效果好于PN,而EN联合PN营养支持较EN或PN能显著改善术后营养状况、提高免疫功能、减少术后并发症、促进胃肠道恢复、缩短住院时间和降低治疗费用,是一种理想的营养支持方案。
Objective To investigate the effect of early enteral and parenteral nutrition on colorectal cancer patients after opera-tion. Methods 120 cases of colorectal cancer patients in our hospital from 2012 December^2014 year in December, were divided into enteral nutrition （Enteral nutrition, EN） group （40 cases）, parenteral nutrition （Parenteral nutrition, PN） group （40 cases） and EN＋PN group （40 cases）. The nutritional index, stress index, immunity index, postoperative complications, time of resumption of gastrointestinal function, hospitalization and treatment cost were compared between three groups. Results After operation, the nu-tritional index （ PA、ALB and TF ）in EN combined with PN group were higher than EN and PN group （P〈0.05）; the stress index （CRP） in EN combined with PN group was lower than EN and PN group（P〈0.05）, in EN group was lower than PN group（P〈0.05）;the immunity index（CD3、CD4 and CD4/CD8） in EN combined with PN group were higher than EN and PN group（P〈0.05）, in EN group was higher than PN group（P〈0.05）;The postoperative complications in EN combined with PN group were less than PN group （P〈0.05）; the time of resumption of gastrointestinal function and hospitalization in EN combined with PN group were less than EN and PN group （P〈0.05）, in EN group was less than PN group（P〈0.05）;the treatment cost in EN combined with PN group were less than EN and PN group （P〈0.05）, in EN group was less than PN group（P〈0.05）. Conclusions The effect of EN on colorectal cancer patients after operation was better than PN. However, EN combined with PN compared with EN and PN on colorectal cancer pa-tients after operation could enhance significantly nutritional status, improve immune function, reduce postoperative complications, shorten the time of resumption of gastrointestinal function and hospitalization and decrease treatment cost. EN combined with PN was an ideal method of nutritional support.
出处
《中国卫生产业》
2015年第8期135-138,共4页
China Health Industry
关键词
肠内营养
肠外营养
结直肠癌
影响
Enteral nutrition
Parenteral nutrition
Colorectal cancer
Effect
