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早发型子痫前期不同治疗方案的临床研究 被引量:2

Clinical Study of Different Treatments for Early Onset Preeclampsia
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摘要 目的研究分析早发型子痫前期不同治疗方案的临床效果,以寻求最佳治疗方案。方法所选对象来源于该院2012年4月—2014年5月接收的87例早发型子痫前期患者,基于治疗方案的不同将其分为3组,即A组、B组以及C组,3组病例数均为29例,A组仅用硫酸镁治疗,B组联合硫酸镁和丹参治疗,C组联合硫酸镁、丹参以及低分子肝素治疗,观察比较3组患者治疗效果。结果 A组和B组、C组比较,24 h PRO(24 h尿蛋白定量)明显要高;C组和A组、B组比较,APTT(活化部分凝血活酶时间)明显要高,差异有统计学意义,即P<0.05。C组和A组、B新生儿存活率比较,前者明显高于后两者,同时C组患者孕周延长天数明显比A组、B组长,差异有统计学意义,即P<0.05。结论经该研究结果分析可知,在早发型子痫前期临床治疗中,联合应用硫酸镁、丹参以及低分子肝素予以治疗,安全有效,获得满意的效果,提高新生儿存活率。 Objective To study the clinical effect of different treatments for early-onset preeclampsia and determines the optimum schem.Methods 87 patients with early-onset preeclampsia admitted to our hospital between April 2012 and May 2014 were selected as the objects and divided according to the different treatment into three groups,group A,group B,group C,29 in each group.Patients in group A,group B,group C received magnesium sulfate treatment,magnesium sulfate and salvia miltiorrhiza therapy,magnesium sulfate,salvia miltiorrhiza,and low molecular heparin therapy,combined therapy of magnesium sulfate,salvia miltiorrhiza,and low molecular heparin observation,respectively.Effects of three groups were compared.Results In group A and group B and group C,24 hour PRO(quantitative) 24 hours urinary protein significantly higher;Compared with group A and group B,group C APTT(activated clotting time live enzymes) significantly high,significant difference statistically significant,that is,P〈0.05.Group C compared with group A and B neonatal survival,the former is significantly higher than the latter two,at the same time patients with gestational age to extend the number of days of group C compared with group A,B,significant difference was statistically significant,that is,P〈0.05.Conclusion The study shows that combined therapy of magnesium sulfate,salvia miltiorrhiza,and low molecular heparin in the treatment of early-onset preeclampsia,is safe,effective and satisfying and it can improve the neonatal survival rate.
作者 孙萌
出处 《中外医疗》 2015年第16期89-90,共2页 China & Foreign Medical Treatment
关键词 早发型 硫酸镁 子痫前期 低分子肝素 丹参 Early onset Magnesium sulfate Preeclampsia Low molecular heparin Salvia miltiorrhiza
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