摘要
目的:观察环孢素A(CsA)治疗小儿难治性肾病综合征的临床治疗效果进行讨论和分析。方法:选择208例小儿难治性肾病综合征的患者作为研究对象。随机分为对照组与干预组两组。其中104例患者为对照组,通过常规的治疗方法;另外104例患者为干预组,通过环孢素A(CsA)的治疗方法。同时,对比干预组和对照组患者在经过治疗后的临床治疗效果以及出现不良反应情况。结果:经过上述实验研究中的数据对比发现,干预组患者的治疗效果明显优于对照组患者的治疗效果,且干预组患者在经过治疗后出现并发症情况的人数也少于对照组患者,两组差异有统计学意义(P<0.05)。结论:对于小儿难治性肾病综合征采用环孢素A(CsA)的治疗方法安全可靠,能够有效减少并发症的发生率,提高患者治疗的总有效率。因此,对于小儿难治性肾病综合征的治疗可以采用环孢素A(CsA)的治疗方式,其治疗效果显著在临床治疗中可以大力推广、使用。
Objective To investigate and analyze the clinical effect of cyclosporineA（ CsA） in the treatment of refractory nephrotic syndrome in children. Method 208 cases of children with refractory nephrotic syndrome were selected as the research object. They were divided into control group and intervention group randomly. 104 patients of control group used routine treatment method,104 patients of intervention group used ciclosporinA（ CsA）.At the same time,compared two groups＇ clinical treatment effect and adverse reactions. Results By comparing the data of the above experimental studies,intervention group＇ s treatment effect was significantly better than control group,intervention group＇s complications after treatment was lower than control group,the difference was statistically significant（ P〈0. 05）. Conclusion CiclosporinA（ CsA） is safe and reliable in the treatment of children with refractory nephrotic syndrome,and can effectively reduce the incidence of complications,improve the total effective rate of treatment. Therefore,the treatment of children with refractory nephrotic syndrome can be treated with cyclosporineA（ CsA）,the treatment effect is significantly in the clinic,it can be vigorously promotion and application
出处
《吉林医学》
CAS
2015年第17期3744-3745,共2页
Jilin Medical Journal
