摘要
目的分析2型糖尿病(T2DM)患者并发骨密度改变的相关危险因素,为早期防治糖尿病并发骨质疏松提供临床资料。方法对2013年7月—2014年7月该院收治的355例病例资料较完整的T2DM含骨密度测定的患者进行回顾性分析,将其按骨密度分为骨量正常组(对照组)、骨含量减少组及骨质疏松组(观察组),分析观察组与对照组T2DM患者中性别、年龄、病程、体重、Hb A1C、空腹C肽、空腹胰岛素、尿微量蛋白定量/肌酐比、血钙、血脂及动脉粥样硬化患病率的差异,进行相关性分析。结果女性、高龄、病程时间长、低BMI、胰岛功能差、微量蛋白尿及动脉粥样硬化的发生率均与糖尿病并发骨质疏松症可能有关,差异有统计学意义(P<0.05),与糖化血红蛋白、血钙、高血脂无明显相关性。结论 T2DM患者女性、高龄、病程长、低体质指数、胰岛功能差、微量蛋白尿、动脉粥样硬化可能为糖尿病合并骨质疏松的相关危险因素。
Objective To analyze the risk factors associated with bone mineral density in patients with type 2 diabetes mellitus （T2DM） and to provide clinical data for early prevention and treatment of osteoporosis. Methods Of July 2013 to 2014 July in our hospital of 355 patients with more complete clinical data of T2DM with determination of bone mineral density （BMD） were retro-spectively analyzed, the according to bone mineral density divided into normal bone mass group （control group）, bone mineral con-tent reduce group and osteoporosis group （observation group）, analysis the observation group and the control group of diabetic pa-tients in sex, age, course of disease, weight, HbA1c, fasting C peptide, insulin, urine trace protein quantitative / creatinine ratio, serum calcium, serum lipids and atherosclerosis of sick rate differences and correlation analysis. Results Female, age, the course of a long time, lower body mass index （BMI）, pancreatic islet function, microalbuminuria and atherosclerosis incidence were with diabetes complicated with osteoporosis may be related, statistical significance （P〈0.05）, and glycosylated hemoglobin, serum calci-um, high blood lipid no significant correlation. Conclusion the risk factors of female, aged, elderly, patients with long term, low body mass index, islet function difference, micro protein urine and atherosclerosis may be associated with the risk factors of dia-betes mellitus complicated with osteoporosis.
出处
《中外医疗》
2015年第19期20-21,共2页
China & Foreign Medical Treatment
关键词
糖尿病
骨质疏松
骨密度
危险因素
Diabetes mellitus
Osteoporosis
Bone mineral density
Risk factors
