摘要
目的探讨经内镜置入覆膜金属支架和非覆膜金属支架治疗恶性胆道梗阻的临床疗效。方法回顾分析我院2007年5月至2012年5月126例经内镜置入金属支架治疗恶性胆道梗阻患者,其中覆膜组59例,无膜组67例。对两组患者的内镜插管成功率、治疗效果、生存时间、支架通畅时间、并发症发生率进行分析和比较。结果内镜插管成功率在覆膜组和无膜组均为100%。覆膜组和无膜组的总引流有效率、术后胰腺炎发生率、术后胆囊炎发生率分别为96.6%vs 94.0%(P>0.05)、13.6%vs 1.5%(P<0.05)、11.9%vs 1.5%(P<0.05)。覆膜组和无膜组的中位生存时间分别为389 d和372 d(P<0.05),中位支架通畅时间分别为368 d和190 d(P<0.05)。结论胆道金属支架可解除中下段胆总管恶性梗阻,延长患者生存时间。覆膜金属支架通畅时间明显优于非覆膜金属支架,术后胰腺炎和胆囊炎发生率均明显高于非覆膜金属支架。
Objective To compare the clinical results of coated and non coated metallic biliary stents in patients with malignant biliary obstruction. Methods One hundred and twenty six patients with malignant bil-iary obstruction were treated with coated stents （59 cases） and non coated stents （67 cases） under endoscopy. The intubation success rate, therapeutic efficacy, survival time, stent patency time and complications rate were analyzed and compared. Results The intubation success rates were 100%in both two groups. The overall drainage rates、pancreatitis rates and cholecystitis rates in coated and non coated groups were 96.6%vs 94.0%（P〉0.05）, 13.6%vs 1.5%（P〈0.05）, 11.9%vs 1.5%（P〈0.05）. The median survival time was 389 days in the coated group, and 372 days in the non coated group（P〉0.05）. The median stent patency time was 368 days in the coated group, and 190 days in the non coated group（P〈0.05）. Conclusion The metallic biliary stent could effectively reduce distal malignant biliary obstruction and prolong the survival time of the patients. The paten-cy time of coated metallic stent could be obviously longer than that of non coated metallic stent. Pancreatitis and cholecystitis could happen more often with coated metallic stent compared with non coated metallic stent.
出处
《现代消化及介入诊疗》
2015年第5期485-488,共4页
Modern Interventional Diagnosis and Treatment in Gastroenterology
关键词
恶性胆道梗阻
覆膜支架
无膜支架
生存时间
通畅时间
Malignant biliary obstruction
Coated metallic stent
Non coated metallic stent
Survival time
Patency time
