摘要
同步辐射具有常规光源不可比拟的优良性能,可用于微量生物矿化样品的物相、结构、形貌和成分研究。本文利用基于同步辐射光源的X射线粉末衍射(SR-XRD)、傅立叶变换红外光谱(SR-FTIR)、X射线荧光分析(SR-XRF)和X射线三维成像,对人体乳腺癌矿化进行了表征。研究表明,乳腺癌矿化的主要矿物物相为碳羟磷灰石,含有Sr、Zn等微量元素,其中砂粒体矿化具有独特的分层结构。研究结果为乳腺癌的病理研究和诊断提供了矿物学参考信息。
Synchrontron radiation performs much better than conventional light source in that it is capable ol ex- amining the mineral phase, crystal structure, morphology and chemical composition of biomineralizaiton samples in a tiny amount. Based on synchrontron radiation, the authors employed several test methods to study human breast cancer calcification, including X-ray diffraction, Fourier transform infrared spectroscopy, X-ray fluores- cence and three-dimensional imaging. According to the results, breast cancer calcification is mainly composed of （carbonated） hydroxylapatite, with trace elements like Sr and Zn. The psammoma body holds special layered structure. These results provide mineralogical information for the pathological study and diagnosis of breast can- cer.
出处
《岩石矿物学杂志》
CAS
CSCD
北大核心
2015年第6期957-962,共6页
Acta Petrologica et Mineralogica
基金
国家自然科学基金资助项目(41272048,40872196)
关键词
同步辐射
荧光
成像
肿瘤
钙化
磷灰石
synchrontron radiation
fluorescence
mapping
tumor
calcification
apatite
