摘要
近年来,中医药治疗慢性便秘的临床研究数量渐多,其所涉及的疗效评价方法及指标主要有Bristol粪便分型及评分、主要症状及单项症状评价、肠动力学疗效、肛门直肠功能评价、盆底肌电图、中医证候疗效、生存质量评价等方面。但目前的中医药疗效的评价方法仍然存在很多问题,如评价症状不全面、缺乏随访及安全性指标、复合结局指标使阳性结果增加、证候分型及评分不统一、实验室指标使用不当等。结合中医药治疗慢性便秘疗效评价发展趋势,提出应选择适用于慢性便秘中医药干预措施的疗效评价指标并充分说明选择的原因和理由,在疗效评价中反映中医药治疗的特色优势,引入病理机制以丰富中医药疗效评价的内涵,为建立和完善高质量的中医治疗慢性便秘临床研究疗效评价体系提供参考。
Clinical researches of Chinese medicine treating chronic constipation are more and more popular.Therapeutic evaluation methods and indexes involved are Bristol stool typing and scoring,main symptoms and single symptom evaluation,intestinal kinetics therapeutic evaluation,anorectal function evaluation,pelvic floor electromyography,Chinese medicine syndromes therapeutic evaluation,life quality evaluation,etc. However,there still remain many problems in current evaluation methods of Chinese medicine effect,such as incomprehensive symptoms evaluation,lacks of follow-up and safety indexes,composite outcome indicators increasing positive results,without united syndrome typing and scoring,misusing laboratory indexes,etc. Combined with the therapeutic evaluation development of Chinese medicine treating chronic constipation,the authors propose suggestions that,therapeutic evaluation indexes applied for chronic constipation Chinese medicine intervention measures should be selected,with the explanation of selecting reasons. In addition,the unique advantages of Chinese medicine treatment ought to be reflected in therapeutic evaluation,and the connotation of Chinese medicine therapeutic evaluation may be enriched by introducing pathological mechanism. This paper may provide reference for establishing and improving high quality therapeutic evaluation system of clinical researches of Chinese medicine treating chronic constipation.
出处
《中医杂志》
CSCD
北大核心
2015年第23期2010-2012,2020,共4页
Journal of Traditional Chinese Medicine
关键词
慢性便秘
中医药疗法
疗效评价体系
chronic constipation
Chinese medicine therapy
therapeutic evaluation system
