摘要
目的:观察枳桔六君子汤加减联合沙美特罗替卡松粉吸入剂治疗支气管哮喘(慢性持续期)的临床疗效。方法:将支气管哮喘(慢性持续期)患者80例随机分为对照组和试验组各40例,对照组给予沙美特罗替卡松粉吸入剂治疗,观察组在此基础上应用枳桔六君子汤加减治疗,两组均连续治疗4周。分别于用药前后观察疾病疗效、哮喘控制水平分级、哮喘控制测试(ACT)积分、PEF占预计值比例变化及不良反应。结果:观察组有效率为92.5%,对照组有效率为75.0%,两组有效率比较,具有显著性差异(P<0.05)。两组患者治疗后哮喘控制水平分级、哮喘控制测试(ACT)积分、PEF占预计值比例均较治疗前明显改善,差异具有统计学差异(P<0.05),组间比较差异显著(P<0.05)。结论:枳桔六君子汤加减联合沙美特罗替卡松粉吸入剂治疗支气管哮喘(慢性持续期)可改善患者中医证候疗效、哮喘控制水平分级、哮喘控制测试(ACT)积分、PEF占预计值比例,疗效显著。
Objective： To observe the clinical effects of Modified Zhijie I.iujunzi Decoction combined with inhalation of Salmeterol Powder on bronchial asthma of chronic persistent stage. Methods ： Patients with bronchial asthma of chronic persistent stage were randomized into control group and observation group, with 40 cases in each group. Control group were given inhalation of Salmet- erol Powder while observation group were added with Modified Zhijie Liujunzi Decoction, with d- weeks of continuous treatment for both groups. The therapeutic effects, level grading of the asthma control, score of ACT and proportion changes of PEF based on the predicted values before and after the treatment were observed, so did the adverse reactions. Results： The effective rate was 92.5% in observation group and 75.0% in control group; there was significant difference （P 〈0.05）. Tbe level grading of the asthma control, score of ACT and proportion of PEF based on the predicted values in both groups after the treatment got markedly improved ; the difference had statistical significance （ P 〈 0. 05 ）, and there also was significant difference between the two groups （ P 〈 0.05 ）. Conclusion ： Modified Zhijie Liujunzi Decoction combined with inhalation of Salmetero｜ Powder has remarkable ther- apeutic effects on bronchial asthma of chronic persistent stage, which can improve the efficacy of the TCM symptoms, level grad- ing of the asthma control, score of ACT and proportion of＇ PEF based on the predicted values.
出处
《河南中医》
2015年第11期2722-2724,共3页
Henan Traditional Chinese Medicine
