摘要
脊髓损伤的中枢性疼痛,是一种严重影响患者生存质量的顽固性疼痛。关于这种痛的发生,R.Melzack和G.Bedbrook提出的中枢兴奋性升高学说,近年来已为一系列实验所逐步证实。戴红等提出它可能主要经由非特异性投射系统上传,造成患者大脑觉醒水平提高所致,并存在一定的受体机制。根据14年的临床观察,归纳出其诊断标准和鉴别诊断标准,其评测应采用莫克吉尔疼痛答卷和视觉模拟评分法进行,治疗宜采用综合疗法。
Central pain(CP)in spinal cord injury(SCI) is a stubborn pain,which effected quality of life of patients seriously.R.Melzack and G.Bedbrook suggested that ascending of excitation of CNS may be the occurrence mechanism of CP in SCI,and had been proved by many experiments these years.Dai Hong et al reported that CP in SCI may be transported through unspecific projection system to brain,caused increasing of awaking level in brain, then occurred.Also suggested new concept about mechanism of receptor.According to clinical observation for 14 years,they summaries the diagnosis standard,differential diagnosis standard and assessment method(MPQ and VAS) of CP in SCI.They also proposed that synthetic therapy may be more suitable for it's treatment.
出处
《中国临床康复》
CSCD
2002年第16期2362-2363,共2页
Chinese Journal of Clinical Rehabilitation
基金
北京市自然科学基金项目(7982016)
