摘要
目的:探讨加味酸枣仁汤对2型糖尿病(T2DM)伴发焦虑抑郁情绪患者疗效的影响。方法:选择T2DM伴发焦虑抑郁情绪患者56例,采用随机数字表法将患者分为对照组和观察组,每组各28例。对照组予以常规促胰岛素分泌、双胍类或α葡萄糖苷酶抑制剂等降糖西药治疗,观察组在对照组的用药基础上予以加味酸枣仁汤,水煎服,1剂/d,两组均连续治疗4周。4周后比较两组患者的血糖控制情况及汉密尔顿焦虑量表(HAMA)和汉密尔顿抑郁量表(HAMD)的评分差异。结果:治疗后两组空腹血糖(FBG)、餐后2小时血糖(2h PG)及糖化血红蛋白(Hb Alc)水平比较,无显著统计学差异(P>0.05);治疗后观察组HAMA、HAMD评分较治疗前和对照组显著降低,差异有统计学意义(P<0.05)。结论:加味酸枣仁汤能有效缓解T2DM患者的焦虑抑郁情绪,提高患者的生存质量。
Objective： To investigate effects of the Suanzaoren decoction on T2DM plus anxiety and depressive symptoms. Methods： 56 cases were selected and randomly divided into the control group and the observation group, with 28 cases in each group. The control group were given conventional insulin secretion, double guanidine kind orα glucosidase inhibitors. The observation group were treated with the Suanzaoren decoction more, 1 agent per day, for 4 weeks. In 4 weeks blood glucose control and HAMA and HAMD scores were compared. Results： After treatment, FBG, 2hPG, and HbAlc in two groups were compared, without significant difference （P〉0.05）; the HAMA and HAMD scores in the treatment group were significantly lower than those in the control group （P〈0.05）. Conclusion： Treating T2DM plus anxiety and depressive symptoms with the Suanzaoren decoction can receive a good effect, is worthy of promotion.
出处
《中医临床研究》
2015年第29期70-71,共2页
Clinical Journal Of Chinese Medicine
关键词
加味酸枣仁汤
2型糖尿病
焦虑
抑郁
疗效
The Suanzaoren decoction
Type 2 diabetes
Anxiety
Depression
Curative effects
