摘要
目的分析牙髓感染患者患牙的产黑色素类杆菌种属以及产黑色素类杆菌与牙髓感染临床症状间的关系,为临床治疗牙髓感染提供指导依据。方法将2012年8月-2013年12月在口腔科就诊的102例牙髓感染患者依临床症状不同分为有症状组95例,无症状组7例,检查并记录所有患者有无患牙疼痛、根尖暗影直径、瘘管和根管内的脓液等临床症状,培养根管中提取的厌氧菌,用多聚酶链反应鉴定产黑色素类杆菌种属。结果有症状组牙髓感染患者,产黑色素类杆菌检出率达80.0%,无症状组检出率仅为28.6%,两组比较差异有统计学意义(P<0.05);分离出的137株产黑色素类杆菌中,解糖菌属达5种,总株数占70.1%,而不解糖菌属仅有2种,总株数占29.9%,两结果比较差异有统计学意义(P<0.05);有牙痛、局部肿胀、根管内渗液等临床症状的患者,产黑色素杆菌的检出率高于无症状患者(P<0.05);有症状组患者牙髓根管中的总菌量也要显著高于无症状组。结论产黑色素类杆菌与牙髓感染的临床症状密切相关,尤以其中的解糖杆菌为主,应引起牙髓根管临床中重视。
OBJECTIVE To investigate the species of the black‐pigmented bacteria isolated from the patient with dental pulp infections and explore the relationship between the black‐pigmented bacteria and the clinical symptoms of dental pulp infections so as to provide guidance for clinical treatment of the dental pulp infections .METHODS A total of 102 patients with dental pulp infections who were treated in department of stomatology from Aug 2012 to Dec 2013 were enrolled in the study and divided into the symptomatic group with 95 cases and the asymptomatic group with 7 cases according to the clinical symptoms .The clinical symptoms of all the patients ,including the toothache ,diameter of shadow of root tip ,and pus in fistula and root canal ,were examined and recorded .The an‐aerobic bacteria extracted from the root canal were cultured ,and the black‐pigmented bacteria were identified by u‐sing polymerase‐chain‐reaction .RESULTS The detection rate of the black‐pigmented bacteria was 80 .0% in the symptomatic group ,28 .6% in the asymptomatic group ,and there was significant difference between the two groups （P〈0 .05） .Among the 137 strains of black‐pigmented bacteria isolated ,there were 5 （70 .1% ） sugar so‐lution species and 2 （29 .9% ） species of Peptoniphilus asaccharolyticus （P〈 0 .05） .The detection rate of the black‐pigmented bacteria was higher in the patients with the clinical symptoms such as toothache ,local swelling , and pus in root canal than in the patients without the clinical symptoms （P〈0 .05）;the bacterial colony counts of the root canal of the symptomatic group were significantly higher than those of the asymptomatic group .CONCLUSION The clinical symptoms of dental pulp infection is closely associated with the black‐pigmented bacteria ,which is dominated by sugar solution species ,and it is necessary for the hospital to pay attention to the root canal .
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2015年第22期5234-5235,5246,共3页
Chinese Journal of Nosocomiology
基金
天津市科技局基金资助项目(TJ53710-C)
关键词
牙髓感染
产黑色素类杆菌
临床症状
解糖菌属
不解糖菌属
Dental pulp infection
Black-pigmented bacteria
Clinical symptom
Sugar solution specie
Peptoniphi-lus asaccharolyticus
