摘要
目的探讨声触诊组织定量技术（VTQ）对浸润性乳腺癌误诊的相关因素,提高VTQ技术对浸润性乳腺癌的诊断价值。方法回顾性分析2013年1月-2014年7月142例经手术病理证实的浸润性乳腺癌病例。所有患者均进行常规超声和VTQ检查。以VTQ检查中乳腺病灶剪切波速度值（SWV）为7.303 m/s为良恶性占位的诊断截断值,根据诊断结果分析比较相关特征。结果 142例浸润性癌中,误诊病例为27例（SWV值〈7.303 m/s）,正确诊断病例为115例（SWV值≥7.303 m/s）。分析浸润性癌的各项特征结果显示肿块最大直径≤10 mm,肿瘤组织学分级I级,淋巴结转移阴性,Ki-67〈14%的浸润性乳腺癌较易被误诊为良性肿块;而患者年龄、肿块深度、ER、PR、HER-2对于浸润性癌的误诊没有明显统计学意义。肿块直径≥10 mm的单纯性黏液癌易被误诊为良性肿块。结论应用VTQ技术评价浸润性乳腺癌：肿瘤最大直径小于10 mm、肿瘤组织学分级Ⅰ级、Ki-67小于14%、淋巴结转移阴性的肿块较易被误诊为良性肿块;肿块直径超过10 mm的单纯性黏液癌易被误诊为良性肿块。
Objective To review causes of diagnostic errors of virtual touch tissues quantification（VTQ） in invasive breast cancer. Methods Pre-operative VTQ of 142 consecutive patients with breast cancer from January 2013 to July 2014 was reviewed.Characteristics of 27 invasive cancer with SWV values 〈7.303 m / s were compared with that of 115 cancer with SWV values ≥7.303 m / s. Results The invasive carcinoma with SWV values 〈7.303 m / s was smaller than 10 mm with grade I tumor histology,no lymph node metastasis and Ki-67 〈14%. There was no significant difference in the patient age, tumor depth, ER, PR, and HER-2 receptors..Mucinous carcinomas larger than 10 mm were more likely to be misdiagnosed as benign tumor. Conclusion Mucinous carcinomas larger than 10 mm and invasive breast cancer smaller than 10 mmwith grade I tumor histology, no lymph node metastasis and Ki-67 〈14% are more likely to be misdiagnosed as benign on VTQ.
出处
《影像诊断与介入放射学》
2015年第5期364-368,共5页
Diagnostic Imaging & Interventional Radiology
基金
上海市浦东新区卫生系统优秀青年医学人才培养计划(PWRq2014-16)
关键词
声触诊组织定量
弹性超声
浸润性乳腺癌
乳腺肿瘤
Virtual touch tissues quantification
Ultrasonic elastography
Invasive breast cancer
Breast diseases
