Notch信号通路与肿瘤发生发展研究进展
摘要
Notch信号转导通路广泛存在,早期发现此通路的调节和激活通过与邻近细胞间的相互作用来调节调控机体各系统细胞和组织器官的分化。
出处
《毒理学杂志》
CAS
CSCD
北大核心
2015年第5期380-382,共3页
Journal of Toxicology
参考文献18
-
1魏秋芳,刘良裕,刘枫,涂志军,吕萌,周锟,余祖滔,潘斌,陈卓.Notch信号通路与肿瘤干细胞及抑制剂研究进展[J].中国药学杂志,2014,49(6):441-448. 被引量:4
-
2Sriuranpong V,Vorges MW, Ravi RK, et al. Notch signaling induces cell cycle arrest in small cell lung cancer cells [ J]. Cancer Res,2001,61 (7):3200-3205. 被引量:1
-
3Haruki N, Kawaguchi KS, Eichenberger S, et al. Dominant negative Notch3 receptor inhibits mitogen activated protein kinase pathway and the growth of human lung cancers [ J]. Cancer Res ,2005,65 (9) :3555-3561. 被引量:1
-
4Zagouras P, Stifani S, Blaumueller CM, et al. Alterations in Notch signaling in neoplastic lesions of the human cervix [J]. Proc Natl Acad Sci U S A,1995(14):6414-6418. 被引量:1
-
5Brzozo M, Role of Notch signaling pathway in gastric cancer patholgenesis [ J ]. Contemp Oncol ( Pozon ) , 2013,17 ( 1 ) : 1-5. 被引量:1
-
6胡娜,宋毅,来卫东,刘琳琳,顾润国.Notch1、Jagged1在肝细胞癌组织中的表达及临床意义[J].中国医药导报,2013,10(19):4-7. 被引量:8
-
7Callahan R, Smith GH. MMTV-induce mammary tumorigen-esis: gene discovery , progression to malignancy and cellular pathway [ J ]. Oncogene, 2000, 19 ( 8 ) : 992- 1001. 被引量:1
-
8Reedijk M, Odorcic S, Chang L, et al. High-level coexpression of Jagl and Notchl is observed in human breast cancer and is associated with poor overall survival [ J ]. Cancer Res, 2005,65 ( 18 ) : 8530-8537. 被引量:1
-
9Zhu H, Zhou XC. Redfield S, et al. Elevated Jagged-1 and Notch-1 expression in high grade and metastatic prostate cancers, He [ J ]. Am Transl Res, 2013,5 (3) : 368 -378. 被引量:1
-
10Patel PN, Yu XM, Jaskula-Sztul R, et al. Hesperetin Activates the Notchl Signaling Cascade, Causes Apoptosis, and Induces Cellular Differentiation in Anaplastic Thyroid Cancer[ J] Ann Surg Oneol, 2014,21Suppl (4) : $497- 504. 被引量:1
二级参考文献93
-
1Miele L. Rational targeting of Notch signaling in breast cancer[J]. Expert Rev Anticancer Ther.2008,8(8): 1197-1202. 被引量:1
-
2Greenburg G. Hay E D. Epithelia suspended in collagen gels can lose polarity and express characteristics of migrating mesenchymal cells[J].J Cell Biol.1982,95(1):333-:l39. 被引量:1
-
3Saitoh M, Shiraki hara T, Miyazono K. Regulation of the stability of cell surface E-cadherin by the proteasome J]. Bi och em Biophys Res Commun,2009,381(4) :560-565. 被引量:1
-
4Nguyen P T, Kudo Y, Yoshida M, et al. N-eadherin expression is involved in malignant behavior of head and neck cancer in relation to epithelial-mesenchymal transition[J]. Histol Histolpathol,2011 ,26(Z): 117-156. 被引量:1
-
5Del Castillo G, Murillo M M, Alvarez-Barrientos A, et al , Autocrine production of TG-F-beta confers rcsist ance 10 apoptosis after an epithelial-mesenchymal transition process in hcpa t ocyr es , role of EGF receptor IigandsJ]]. Exp Cell Res, 2006, IZ( 15) :2860-2871. 被引量:1
-
6Mathew S, Fu L, Hasebe T, et al. Tissue-dependent induction of apopt osis by matrix met a l loprnt ei nas c stromclysin-3 during amphibian metamorphosis[J]. Birth Defects Bes C Embryo Today,2010,90(l) :55-66. 被引量:1
-
7Vincent-Salomon A, Lucchesi C, Gruel N, et al. Integrated genomic and transcr iptomic analysis of ductal carcinoma in situ of the br casrj]]. Clin Cancer Res,ZOOS, 14(7): 19SG 1965. 被引量:1
-
8Hollier B G, Evans K, Mani S A. The epithelial-to?mesenchymal transition and cancer stem cells: a coalition against cancer thernpiesf]].J Mammary Gland Bioi Neoplasia , 200. II (1) :29-4:3. 被引量:1
-
9Sarrio D, PalacoisJ, Hergueta?-Redondo M, e: al. Functional characterization of E and P-cadhcrin in invasive breast cancer cells[J]. BMC Cancer,Z009,9(9) :74. 被引量:1
-
10Leong K G, Nicssen K, Kulic I. et ul ,Jaggedl-mcdiatec1 Notch activation induces epithelial-to-mesenchymal transition through slug-induced repression of E-cadherin[J].J Exp VIed.2007 .20?1 (2): Z935-2918. 被引量:1
共引文献25
-
1郭鱼波,王春晖,裴晓华.乳腺癌细胞上皮间质转化的分子机制及其防治的研究进展[J].中国肿瘤,2018,27(12):933-943. 被引量:17
-
2张晓菊,安云霞,汪铮,任红岩,时军,马希涛.上皮间质转化及CD146和N-cadherin在判定肺腺癌EGFR-TKI获得性耐药中的作用[J].中华实用诊断与治疗杂志,2014,28(9):849-851. 被引量:5
-
3刘宇,徐海帆.Notch信号通路与乳腺癌的研究进展[J].中国医药指南,2014,12(30):54-56. 被引量:1
-
4王波,张彤,王群.DLIA/Notch信号通路对乳腺癌化疗药物转运及化疗耐药性影响的实验研究[J].中国医药,2015,10(3):389-391.
-
5张秀青,李万胜,沈素朋,邝钢,董稚明.卵巢上皮性癌中Notch-1和Jagged-1的表达及临床意义[J].现代肿瘤医学,2015,23(7):977-980. 被引量:4
-
6葛晓晴,杨鲲鹏,任景丽,王旭广,郭晓峰,乔梦晗,张进.E-钙黏附蛋白和E盒结合锌指蛋白2在非小细胞肺癌中表达及预后[J].中华实用诊断与治疗杂志,2015,29(4):379-381. 被引量:4
-
7邓萌,王磊,翟保平.乳腺癌干细胞分选与鉴定方法研究进展[J].中华实用诊断与治疗杂志,2015,29(5):429-431. 被引量:2
-
8张慧峰,余海波.核受体共激活因子在肝细胞肝癌中表达及意义[J].中华实用诊断与治疗杂志,2015,29(11):1068-1070. 被引量:1
-
9马睿锐,贡海兵,龚健,徐彬.上皮细胞间质化预测胰腺癌预后的价值[J].世界华人消化杂志,2016,24(5):686-691.
-
10曹品容,孔应利,罗燕梅,黄维,许建华,叶敏.PI3K-Akt-mTOR信号通路抑制剂的耐药机制研究进展[J].中国药学杂志,2016,51(4):253-258. 被引量:3
-
1黄荣蓉.整体护理在门诊止痛治疗患者中的应用[J].河北医药,2011,33(17):2696-2697.
-
2赵惠芳,易忠群,程新宪,魏瑞全.肿瘤患者血清TNF-α、IL-6、IL-8检测及意义[J].西北国防医学杂志,1998,19(1):27-28. 被引量:4
-
3万冬挂.如何防治乳腺癌术后上肢水肿?[J].中老年保健,1997(1):47-47.
-
4赵腾,郑运松.磁共振成像技术在宫颈癌转移性淋巴结的研究进展[J].现代医用影像学,2016,25(5):805-808.
-
5方伟岗.精准医学 让民众不再谈癌色变[J].农民文摘,2016,0(10):48-49.
-
6郭晓东,曹丹庆.脑转移瘤的CT诊断 (附100例分析)[J].中国医学影像技术,1989,5(1):14-16. 被引量:1
-
7张洁,任翠,薛华丹,周海龙,孙照勇,金征宇.弥散加权成像对宫颈癌淋巴结转移的诊断价值[J].中国医学科学院学报,2014,36(1):73-78. 被引量:19
-
8吴晨晨,郭莉,周惠,何玮,潘璐璐,万巧琴.1例重症癌转移患者围术期低体温的预防及护理[J].中华现代护理杂志,2012,18(13):1594-1596. 被引量:2
-
9病例50:54岁女性昏厥,心电图ST段异常[J].高血压杂志,2006,14(1):71-73.
-
10病例50:54岁女性昏厥,心电图ST段异常[J].高血压杂志,2005,13(11):743-743.