摘要
为了探讨肛周脓肿致病菌的分布、变迁及药敏变化特点，回顾性分析2012～2014年行脓液细菌培养加药敏试验的174例肛周脓肿患者的细菌谱及药敏变化特点。结果显示，肛周脓肿细菌谱构成比及耐药率差异均无统计学意义。174例培养有细菌生长145例，其中大肠埃希菌、肺炎克雷伯菌分别占79．59％、10．20％；大肠埃希菌检出比例分别为75．00％、82．40％、81．80％，差异无统计学意义。致病菌对氨苄西林、磺胺类、喹诺酮和第一、二、三代头孢菌素类抗生素有着较高的耐药性，对阿米卡星、头孢美唑、β-内酰胺酶抑制剂和碳青酶烯类有着较高的敏感性，且细菌对抗生素敏感度呈下降趋势。结果表明，大肠埃希菌仍然是肛周脓肿主要致病菌，3年内细菌构成无明显改变，病原菌对抗生素的耐药率无明显变化。
This study was to investigate the distribution,variation and drug-sensitivity change feature,ret- roscpectively analyzed the bacteria spectrum and drug-sensitivity change in 174 patients with perianal ab- scess from 2012 to 2014 yr..As results,in composition ratio of bacteria spectrum and drug-resistance rate there all was no statistical significance ; among the 174 cases 145 were positive in bacteria culture, E,coli. and klebsiella pneumoniae accounted 79.59% and 10.20//00, respectivelly, detection ratio of E,coli. was 75.0% ,82.40% and 81.8%, respectively,had no statistical differenee;pathogen had higher drug-resistance to ampicillin, sulfanilamide-like drugs, quinolone and cephalosporin of the 1st, 2nd, 3rd generation, higher sensitivity to amikacin cefmetazole,13-1actamase inhibitor, and carbapenems, as well the sensitivity of bacte- ria to antibiotics became descending trend.Results show that E,coli. is main pathogen to perianal abscess yet ; within 3 years bacteria composition ratio has no distinct change, drug-resistance rate of bacteria to anti- biotics had also no significant change.
出处
《中国肛肠病杂志》
2015年第8期22-24,共3页
Chinese Journal of Coloproctology
关键词
肛周脓肿
细菌耐药性
药敏试验
Perianal abscess ~ Bacteria drug-resistance ~ Drug-sensitivity test
