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泵入利尿剂改善慢性肾小球肾炎水肿症状的疗效分析 被引量:2

Pumped into Improving the Efficacy of Diuretics Edema Symptoms of Chronic Glomerulonephritis
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摘要 目的:探讨泵入利尿剂改善慢性肾小球肾炎水肿症状的疗效。方法:选择2011年7月-2014年2月在我院住院治疗的慢性肾小球肾炎患者172例,根据随机抽签原则分为治疗组86例与对照组86例,对照组给予常规综合治疗,治疗组在对照组治疗的基础上给予泵入利尿剂进行治疗,两组治疗观察时间为3个月。结果:治疗后治疗组与对照组的总有效率分别为97.7%和84.9%,治疗组高于对照组(P〈0.05)。治疗后治疗组与对照组的尿蛋白定量为(0.88±0.23)g/24h和(1.09±0.49)g/24h,都明显低于治疗前的(1.33±0.45)g/24h和(1.35±0.38)g/24h(P〈0.05),组间对比差异具有统计学意义(P〈0.05)。治疗后治疗组与对照组的水肿症状评分分别为(0.98±0.45)分和(1.89±0.32)分(P〈0.05),都明显低于治疗前的(4.56±0.56)分和(4.61±0.44)分,同时组间对比差异也有统计学意义(P〈0.05)。两组治疗后的血肌酐含量都明显低于治疗前(P〈0.05),同时治疗后组间对比差异明显(P〈0.05)。结论:泵入利尿剂治疗能有效改善慢性肾小球肾炎患者的水肿症状,增加尿蛋白定量,促进肾功能的恢复,从而提高总体治疗疗效。 Objective: To investigate the diuretic pumped into improving chronic glomerulonephritis symptoms of edema effect.Methods:July 2011 to February 2014 in our hospital treated 172 cases of patients with chronic glomerulonephritis,according to the principle of random draw into the treatment group of 86 patients and the control group of 86 patients in the control group received conventional treatment,The treatment group received the pump on the basis of the control group on the diuretic treatment,and after treatment observation period of 3 months.Results:After treatment,the treatment group and the control group,an efficiency of 97.7% and 84.9% respectively,the total effective rate was significantly higher(P〈0.05) treatment groups.Urinary protein treatment group and the control group was(0.88±0.23)g/24 h and(1.09±0.49)g/24 h,were significantly lower than before treatment(1.33±0.45)g/24 h and(1.35±0.38)g/24h(P〈0.05),compared to differences between the two groups was statistically significant(P〈0.05).The treatment group and the control group edema symptom score was(0.98±0.45)and(1.89±0.32) points points(P〈0.05),were significantly lower than before treatment of(4.56±0.56) points and(4.61±0.44) points,compared to between-group differences at the same time there was statistically significant(P〈0.05).After treatment,serum creatinine content were significantly lower than before treatment(P〈0.05),while serum creatinine content after treatment treatment group was significantly lower than the control group(P〈0.05).Conclusion:The pumped into diuretic therapy can improve symptoms of edema in patients with chronic glomerulonephritis,increased urinary protein excretion,and promote the recovery of renal function,and thereby improve overall treatment efficacy.
出处 《中国医药导刊》 2015年第10期1052-1054,共3页 Chinese Journal of Medicinal Guide
关键词 利尿剂 慢性肾小球肾炎 水肿 尿蛋白定量 Diuretics Chronic glomerulonephritis Edema Urine protein
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