摘要
Pd（CH3CN）2Cl2与硫酰胺配体形成的金属络合物为催化剂应用到Csp2-Csp3成键的Negishi交叉偶联反应中去.结果表明,在室温下伯碳和仲碳的烷基锌试剂均可以很好地兼容,不同的芳基碘化物也得到兼容.产率在75%-90%之间,实现了Csp2-Csp3的Negishi交叉偶联反应。
The metal complex of Pd （CH3CN）2Cl2 and sulfur amide ligands as the catalyst was applied to the Csp^2- Csp^3 negishi bond formation coupling reactions. The resuct shows that the primary and secondary alkyl zinc reagent could be tolerated, and different aryl iodide could be tolerated in room temperature. The production rate is between 75% and 90%, and the Csp^2-Csp3 negishi cross-coupling reactions are achieved.
出处
《河南科学》
2015年第10期1728-1731,共4页
Henan Science
关键词
钯
硫酰胺
芳基碘
烷基锌试剂
交叉偶联
palladium： sulfur amide
ArI
Alkyl-Znreagents
cross-coupling
