摘要
目的研究醉鱼草科醉鱼草属植物醉鱼草茎叶的化学成分。方法采用AB-8大孔吸附树脂、硅胶层析柱色谱、Sephadex LH-20凝胶柱色谱及重结晶等方法,对醉鱼草茎叶的正丁醇部位进行分离和纯化,根据理化性质及波谱数据对得到的化合物进行结构鉴定。结果从醉鱼草茎叶60%乙醇提取物中正丁醇部位分离得到10个化合物,分别鉴定为：蒙花苷（1）、芦丁（2）、木犀草素（3）、槲皮素（4）、芹菜素（5）、橙皮素（6）、红景天苷（7）、齐墩果酸（8）、β-谷甾醇（9）、胡萝卜苷（10）。结论化合物2~7为首次从该植物中分离得到。
Objective To investigate the anti-H5N1 activities and chemical constituents from stems and leaves of Buddleja lindleyana Fort.. Methods Constituents were separated through AB-8 macroporous resin,chromatography of silica gel,Sephadex LH-20 and recrystallization. Structures of the compounds were identified by analysis of physicochemical properties and spectral data.Results Ten compounds were isolated and identified as linarin（1）,rutin（2）,luteolin（3）,quercetin（4）,apigenin（5）,hesperetin（6）,salidroside（7）,oleanolic acid（8）,β-sitosterol（9）,and daucosterol（10）,respectively. Conclusion Compounds 2-7 were obtained from this plant for the first time.
出处
《国际药学研究杂志》
CAS
CSCD
北大核心
2015年第5期634-636,共3页
Journal of International Pharmaceutical Research
关键词
醉鱼草
化学成分
黄酮类
Buddleja lindleyana Fort.
chemical constituents
flavonoids
