摘要
目的:观察参麦注射液联合纳洛酮治疗烧伤性休克的疗效。方法:选择2011年3月—2014年12月在本院接受诊治的烧伤性休克患者100例,根据随机数字表法分为治疗组和对照组,每组50例。两组均于患者入院后采用常规烧伤性休克治疗。对照组给予纳洛酮0.8 mg加入生理盐水20 m L静脉滴注,治疗组在对照组的基础上给予参麦注射液30 m L加入50 m L葡萄糖注射液中静脉滴注。结果:治疗组有效率90.00%,对照组有效率74.00%,治疗组优于对照组(P<0.05);治疗组意识恢复时间、心率复常时间、出汗停止时间、紫绀消退时间、尿量复常时间、肢厥消失时间显著短于对照组(P<0.05);治疗组纠正休克时间及首次血压回升时间均显著短于对照组(P<0.05);两组不良反应比较,无统计学意义(P>0.05)。结论:参麦注射液联合纳洛酮治疗烧伤性休克疗效显著。
Objective： To observe the clinical curative effect of Shenmai Injection（ SMI） in combination with naloxone on burning shock. Methods： One hundred patients with burning shock who were treated in our hospital between March of 2011 and Dec. of 2014 were divided into the treatment group and the control group according to random number table method,with 50 cases in each group.All the patients were first given routine treatment for burning shock. Then the ones in the control group were added intravenous infusion of 0. 8 mg of naloxone together with 20 m L of normal saline,while the ones in the g treatment roup were added intravenous infusion of 30 ml of SMI together with 50 m L of glucose injection. Results： The effective rate of the treatment group was 90. 00%,while that of the control group was 74. 00%; And the treatment group was better than the control group（ P〈0. 05）. The consciousness recovery time,heart rate recovery time,sweating stopping time,cyanosis disappearing time,urine volume recovery time,and limb spasm disappearing time of the treatment group were all much shorter than those of the control group（ P〈0. 05）. The correcting shock time and initial blood pressure recovering rising time of the treatment group were all much shorter than those of the control group（ P〈0. 05）. In terms of adverse reactions,the differences between the two groups had no statistical significance（ P〈0. 05）. Group consciousness,after time,limb then time was significantly shorter than the control group（ P〈0. 05）; in the treatment group and the rise times are significantly shorter than the control group（ P〈0. 05）; adverse events between the two groups,no significant（ P〈0. 05）.Conclusion： SMI in combination with naloxone has remarkable clinical curative effect on burning shock.
出处
《河南中医》
2015年第10期2542-2544,共3页
Henan Traditional Chinese Medicine
关键词
烧伤性休克
参麦注射液
纳洛酮
burning shock
Shenmai Injection（SMI）
naloxone
