摘要
目的：研究分析他汀类药物治疗老年急性肾损伤患者的临床效果.方法：选取2012年11月-2014年11月收治的老年急性肾损伤患者102例,随机分为A、B、C3组,每组34例,A组给予20mg阿托伐他汀治疗,B组给予40mg阿托伐他汀治疗,C组给予常规治疗,对比3组临床效果.结果：B组Scr、TC、TG水平下降程度与A、C两组相比,差异显著（P 〈0.05）;治疗后,3组细胞因子水平均显著低于治疗前,差异显著（P 〈0.05）;B组细胞因子水平下降程度显著优于A、C组,差异显著（P 〈0.05）.结论：较大剂量他汀类药物治疗老年急性肾损伤具有显著的临床效果,值得推广.
Objective:To Analyze the clinical effects of statins on elderly patients with acute kidney inju-ry.Methods:Select 102 elderly patients with acute kidney injury deceived during the period from November 2012 to November 2014 and randomly divided into them into group A,group B,and group ,with 34 cases in each group,group A was treated with 20mg of atorvastatin ,group B received 40mg of atorvastatin ,group C received conventional therapy,compare the clinical effect in the three groups.Results:To compare the de-creasing level of Scr,TC,TG were obvious in group B with that in groupA,and group C ,the difference was significant (P<0.05);After treatment,the level of cytokine of the 3 groups was significantly lower than before ,the difference was significant (P<0.05);the decreasing of cytokine in group B was significantly bet-ter than that in group A and group C,the differences were significant (P<0.05).Conclusion:It is effective to treat elderly patients with acute kidney inj ury with relatively large dosage of statins,it is worthy of clinical promotion.
出处
《数理医药学杂志》
2015年第11期1710-1711,共2页
Journal of Mathematical Medicine
关键词
他汀类药物
老年急性肾损伤
临床疗效
statins
elderly patients with acute kidney injury
clinical efficacy
