摘要
目的:探讨时间分辨荧光分析技术(DELFIA)筛查新生儿先天性甲状腺功能低下的的准确率。方法:回顾性分析我院2008年1月至2013年5月收治的20000例新生儿的临床资料。分别利用酶联免疫吸附法(ELISA)和时间分辨荧光分析技术检测新生儿足跟血中三碘甲腺原氨酸(T3)、四碘甲腺原氨酸(T4)及促甲状腺素(TSH)水平。比较两种检测方法的准确率。结果:DELFIA初次筛查CH的准确性明显高于ELISA。对召回的新生儿进行TSH复测,DELFIA对TSH≥20 m U/L的检测准确率最高,差异具有统计学意义(P<0.05)。结论:DELFIA在筛查先天性甲状腺功能低下中具有较高的应用价值,可作为临床筛查的首选方法。
Objective： To analyze the application of time-resolved immunoassay （DELFIA） in the screening of congenital hy- pothyroidism （CH）. Methods： The clinical data of 20,000 cases of neonatal who were born in our hospital from January 2008 to May 2013 were retrospectively analyzed. Results： DELFIA first screening accuracy obviously higher than that of ELISA, statistically signifi- cant difference （P〈0.05）. DELFIA review detection rate higher than that of ELISA, statistically significant difference （P〈0.05）. Conclu- sion： DELFIA has high application value in screening of congenital hypothyroidism.
出处
《现代生物医学进展》
CAS
2015年第29期5658-5660,共3页
Progress in Modern Biomedicine
