摘要
背景:膝关节软骨损伤后很难愈合,是临床上亟需解决的重要课题。目的:总结滑膜间充质干细胞在膝关节软骨损伤治疗上的优越性。方法:用英文主题词"Knee Joint,Cartilage,Synovial Membrane,Tissues,Injuries,Repair"在Pub Med数据库中检索2005年8月至2015年8月文献总共625篇。采纳并分析滑膜间充质干细胞治疗膝关节软骨损伤文献48篇。排除其他非滑膜间充质干细胞及非膝关节软骨损伤治疗的相关文章,保留35篇文章进行综述。结果与结论:应用滑膜间充质干细胞治疗膝关节软骨损伤,能够获得更加理想的治疗效果,损伤组织本身固有的间充质干细胞是修复损伤组织的最佳种子细胞。
BACKGROUND： Knee cartilage injury is difficult to heal, which is an urgent clinical problem to solve. OBJECTIVE： To summarize the advantages of synovial mesenchymal stem cells in the treatment of knee cartilage injury. METHODS： A computer-based search of Pub Med was performed for articles related to synovial mesenchymal stem cells for knee cartilage injury using the keywords of ＂knee joint, cartilage, synovial membrane, tissues, injuries and repair＂. A total of 48 articles were retrieved initially, and 35 articles were included in result analysis. RESULTS AND CONCLUSION： Synovial mesenchymal stem cells for treatment of knee cartilage injury can achieve more ideal outcomes. Mesenchymal stem cells inherent in the damaged tissue are the optimal seed cells for tissue repair.
出处
《中国组织工程研究》
CAS
北大核心
2015年第36期5886-5891,共6页
Chinese Journal of Tissue Engineering Research
基金
贵州省省长资金(贵州省科技教育领导小组)[黔省专合字(2006)46号]~~
